SCHEMBL29697024

SCHEMBL29697024

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 2/20 0.45
▸ MC4R P32245 3/20 0.44
▸ GLP1R P43220 4/20 0.43
▸ SCTR P47872 1/20 0.43
▸ NPY4R P50391 5/20 0.43
▸ NPY1R P25929 4/20 0.43
▸ NPY2R P49146 4/20 0.43
▸ NPY5R Q15761 4/20 0.43
▸ NMUR2 Q9GZQ4 2/20 0.43
▸ NMUR1 Q9HB89 2/20 0.43
▸ OPRM1 P35372 1/20 0.42
▸ FOLH1 Q04609 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31440231 0.90 KISS1R (0.52) KISS1RNPY4RNPY1RNPY2RNPY5R
SCHEMBL29958548 0.90 NPY4R (0.49) KISS1RNPY4RNPY1RNPY2RNPY5R
SCHEMBL30663358 0.89 FOLH1 (0.46) MC4RNPY4RNPY1RNPY2RNPY5R
SCHEMBL29476475 0.89 FOLH1 (0.45) MC4RGLP1RSCTRNPY4RNPY1R
SCHEMBL30152128 0.89 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29420164 0.89 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29697043 0.88 NPY4R (0.53) KISS1RNPY4RNPY1RNPY2RNPY5R
SCHEMBL29697085 0.88 NPY4R (0.53) KISS1RNPY4RNPY1RNPY2RNPY5R
SCHEMBL29519652 0.88 NPY4R (0.54) KISS1RGLP1RSCTRNPY4RNPY1R
SCHEMBL29519546 0.88 NPY4R (0.45) MC4RGLP1RSCTRNPY4RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861268-B Cell penetrating peptides and methods of making and using the same 恩特拉达治疗学股份有限公司 2025-04-01 — — CN disclosed
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2025-01-09 — — US disclosed
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2022-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 KISS1R 2778/4885MC4R 3237/4885GLP1R 751/4885
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 KISS1R 2778/4885MC4R 3237/4885GLP1R 751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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