Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 2/20 | 0.62 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.57 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.55 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20435026 | 1.00 | PRKACA (0.62) | PRKACADNPH1ADORA1ADORA3SLC29A1 | |
| SCHEMBL20435021 | 1.00 | PRKACA (0.62) | PRKACADNPH1ADORA1ADORA3SLC29A1 | |
| SCHEMBL26292088 | 0.93 | PRKACA (0.61) | PRKACADNPH1ADORA1ADORA3SLC29A1 | |
| SCHEMBL20435008 | 0.92 | ADORA1 (0.66) | PRKACADNPH1ADORA1ADORA3SLC29A1 | |
| SCHEMBL20435005 | 0.92 | ADORA1 (0.66) | PRKACADNPH1ADORA1ADORA3SLC29A1 | |
| SCHEMBL29697175 | 0.92 | ADORA1 (0.66) | PRKACADNPH1ADORA1ADORA3SLC29A1 | |
| SCHEMBL20434989 | 0.91 | DNPH1 (0.62) | DNPH1ADORA1ADORA3SLC29A1TP53 | |
| SCHEMBL20434976 | 0.91 | DNPH1 (0.62) | DNPH1ADORA1ADORA3SLC29A1TP53 | |
| SCHEMBL24505727 | 0.88 | ADORA1 (0.65) | DNPH1ADORA1ADORA3SLC29A1TP53 | |
| SCHEMBL20434975 | 0.85 | SLC29A1 (0.57) | DNPH1ADORA1ADORA3SLC29A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12129273-B2 | Compound with analgesic effect for use in prevention and treatment of pain | ACADEMIA SINICA (TW) | 2024-10-29 | — | — | US | disclosed |
| US-20240010669-A1 | COMPOUND WITH ANALGESIC EFFECT FOR USE IN PREVENTION AND TREATMENT OF PAIN | ACADEMIA SINICA (TW) | 2024-01-11 | — | — | US | disclosed |
| US-11753432-B2 | Compound with analgesic effect for use in prevention and treatment of pain | ACADEMIA SINICA (TW) | 2023-09-12 | — | — | US | disclosed |
| EP-3573996-B1 | COMPOUND WITH ANALGESIC EFFECT FOR USE IN PREVENTION AND TREATMENT OF PAIN | ACADEMIA SINICA (TW) | 2022-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240010669-A1 | COMPOUND WITH ANALGESIC EFFECT FOR USE IN PREVENTION AND TREATMENT OF PAIN | ADORA2B, ADORA1, ADORA3 | PRKACA 2470/4885DNPH1 613/4885ADORA1 2/4885 |
| US-12129273-B2 | Compound with analgesic effect for use in prevention and treatment of pain | ADORA2B, ADORA1, ADORA3 | PRKACA 2470/4885DNPH1 613/4885ADORA1 2/4885 |
| US-11753432-B2 | Compound with analgesic effect for use in prevention and treatment of pain | ADORA2B, ADORA1, ADORA3 | PRKACA 2919/4885DNPH1 511/4885ADORA1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.