SCHEMBL29697130

SCHEMBL29697130

Cc1ccc(-c2cccc(Cl)c2)c(-c2ccc(N=Nc3cc(S(=O)(=O)O)c4ccccc4c3N)cn2)c1

nearest known ligand 0.85

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SENP2 Q9HC62 2/20 0.55
▸ SENP1 Q9P0U3 2/20 0.55
▸ SUMO2 P61956 1/20 0.55
▸ SUMO1 P63165 1/20 0.55
▸ SENP7 Q9BQF6 1/20 0.55
▸ SENP3 Q9H4L4 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14997154 1.00 SENP2 (0.55) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL18044193 1.00 SENP2 (0.55) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL14988777 0.99 SENP2 (0.55) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL14988773 0.99 SENP2 (0.55) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL15120211 0.92 SENP2 (0.56) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL18044201 0.92 SENP2 (0.56) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL29697142 0.92 SENP2 (0.56) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL15120210 0.92 SENP2 (0.60) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL18044289 0.92 SENP2 (0.60) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL29697122 0.92 SENP2 (0.60) SENP2SENP1SUMO2SUMO1SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118434418-A Composition for improving cardiac function 国立大学法人京都大学 2024-08-02 — — CN claimed
CN-114599370-A Pharmaceutical composition for protecting cartilage 国立大学法人京都大学 2022-06-07 — — CN claimed
US-20250057823-A1 COMPOSITION FOR IMPROVING CARDIAC FUNCTION KYOTO UNIVERSITY (JP) 2025-02-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250057823-A1 COMPOSITION FOR IMPROVING CARDIAC FUNCTION TNNI3, NPPA, TNNT2 SENP2 3538/4885SENP1 2852/4885SUMO2 4148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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