SCHEMBL29453074

SCHEMBL29453074

C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.65
OPRM1 P35372 3/20 0.58
OPRD1 P41143 1/20 0.52
REN P00797 1/20 0.52
ANPEP P15144 1/20 0.51
LNPEP Q9UIQ6 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496921 0.91 SLC6A2 (0.66) SLC6A2OPRM1OPRD1
SCHEMBL30953189 0.88 SLC6A2 (0.73) SLC6A2OPRM1RENANPEPLNPEP
SCHEMBL29713420 0.87 SLC6A2 (0.62) SLC6A2OPRM1OPRD1REN
SCHEMBL31257016 0.86 SLC6A2 (0.61) SLC6A2OPRM1OPRD1RENANPEP
SCHEMBL29591343 0.86 SLC6A2 (0.63) SLC6A2OPRM1OPRD1ANPEPLNPEP
SCHEMBL30209473 0.86 SLC6A2 (0.61) SLC6A2OPRM1
SCHEMBL31676579 0.86 OPRM1 (0.63) SLC6A2OPRM1OPRD1
SCHEMBL31059337 0.85 SLC6A2 (0.59) SLC6A2OPRM1OPRD1
SCHEMBL30424040 0.85 SLC6A2 (0.62) SLC6A2OPRM1OPRD1REN
SCHEMBL29571797 0.85 OPRM1 (0.74) SLC6A2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363043-B1 COMPOSITIONS FOR USE IN METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2026-04-22 EP disclosed
US-20260062413-A1 KINASE INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES OHIO STATE INNOVATION FOUNDATION (US) 2026-03-05 US disclosed
US-20260015420-A1 CD47 BINDING AGENTS CENTESSA PHARMACEUTICALS UK LTD (GB) 2026-01-15 US disclosed
EP-4228623-B1 KINASE INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES OHIO STATE INNOVATION FOUNDATION (US) 2025-12-03 EP disclosed
US-20250339680-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2025-11-06 US disclosed
US-12448375-B2 Kinase inhibitors for the treatment of neurodegenerative diseases OHIO STATE INNOVATION FOUNDATION (US) 2025-10-21 US disclosed
US-12421310-B2 CD47 binding agents CENTESSA PHARMACEUTICALS (UK) LIMITED (GB) 2025-09-23 US disclosed
US-12383738-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields NOVOCURE GMBH (CH) 2025-08-12 US disclosed
EP-4582452-A1 NOVEL ANTI-PD-L1 CHIMERIC ANTIGEN RECEPTOR, AND IMMUNE CELLS EXPRESSING SAME Korea Research Institute of Bioscience and Biotechnology (KR) 2025-07-09 EP disclosed
US-20250001166-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2025-01-02 US disclosed
WO-2024049161-A1 NOVEL ANTI-PD-L1 CHIMERIC ANTIGEN RECEPTOR, AND IMMUNE CELLS EXPRESSING SAME 한국생명공학연구원 2024-03-07 WO disclosed
CN-117580614-A Compositions and methods for increasing sensitivity of cancer cells to alternating electric fields 诺沃库勒有限责任公司 2024-02-20 CN disclosed
EP-4228623-A1 KINASE INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES Ohio State Innovation Foundation (US) 2023-08-23 EP disclosed
US-20230001193-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS BIOPHARMA CREDIT PLC (GB) 2023-01-05 US disclosed
CN-112979812-B An isolated binding protein comprising an SCCA antigen binding domain 东莞市朋志生物科技有限公司 2022-11-04 CN disclosed
US-20220340568-A1 KINASE INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES OHIO STATE INNOVATION FOUNDATION 2022-10-27 US disclosed
EP-4010326-A1 KINASE INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES Ohio State Innovation Foundation (US) 2022-06-15 EP disclosed
WO-2022081552-A1 KINASE INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES OHIO STATE INNOVATION FOUNDATION (US) 2022-04-21 WO disclosed
US-11291286-B2 Cosmetic compositions with a micro-mesh structure ELC MANAGEMENT LLC (US) 2022-04-05 US disclosed
US-11285165-B2 Selective high-affinity polydentate ligands and methods of making such LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2022-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12448375-B2 Kinase inhibitors for the treatment of neurodegenerative diseases BRDT, BRD3, BRD1 SLC6A2 4684/4885OPRM1 4443/4885OPRD1 3952/4885
US-20260062413-A1 KINASE INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES BRD3, SMN1; SMN2, HDAC1 SLC6A2 4551/4885OPRM1 3283/4885OPRD1 2504/4885
US-11285165-B2 Selective high-affinity polydentate ligands and methods of making such CD44, FCGR3B, FCGR2A SLC6A2 1606/4885OPRM1 2021/4885OPRD1 2255/4885
US-20220340568-A1 KINASE INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES BRDT, BRD3, BRD2 SLC6A2 4703/4885OPRM1 4432/4885OPRD1 3987/4885
US-20260015420-A1 CD47 BINDING AGENTS CD47, FCGR2A, FCGR3B SLC6A2 3002/4885OPRM1 3641/4885OPRD1 1344/4885
US-11291286-B2 Cosmetic compositions with a micro-mesh structure CD44, CUTA, MSH6 SLC6A2 2777/4885OPRM1 224/4885OPRD1 2825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.