Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 2/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM1 | P22735 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3898037 | 1.00 | BTK (0.39) | BTKSMN1; SMN2MMP2ANPEPHSD17B10 | |
| SCHEMBL3894190 | 0.90 | MMP2 (0.38) | BTKMMP2ANPEPCYP1A2POLB | |
| SCHEMBL14090197 | 0.90 | MMP2 (0.38) | BTKMMP2ANPEPCYP1A2POLB | |
| SCHEMBL29697307 | 0.84 | AGTR2 (0.36) | MMP2ANPEPAGTR2KCNA3CHRM1 | |
| SCHEMBL22980663 | 0.84 | AGTR2 (0.36) | MMP2ANPEPAGTR2KCNA3CHRM1 | |
| SCHEMBL25235410 | 0.84 | BTK (0.54) | BTKSMN1; SMN2MMP2ANPEPHSD17B10 | |
| SCHEMBL7736016 | 0.84 | BTK (0.54) | BTKSMN1; SMN2MMP2ANPEPHSD17B10 | |
| SCHEMBL7729066 | 0.84 | BTK (0.54) | BTKSMN1; SMN2MMP2ANPEPHSD17B10 | |
| SCHEMBL7722234 | 0.84 | BTK (0.54) | BTKSMN1; SMN2MMP2ANPEPHSD17B10 | |
| SCHEMBL15297652 | 0.84 | BTK (0.54) | BTKSMN1; SMN2MMP2ANPEPHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010080-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Artios Pharma Limited (GB) | 2022-06-15 | — | — | EP | disclosed |