SCHEMBL29697484

SCHEMBL29697484

CC(C)(C)[C@@H](C(=O)O)N1C(=O)c2c(F)c(F)c(F)c(F)c2C1=O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
CSNK2A1 P68400 1/20 0.36
PDE4A P27815 2/20 0.34
PDE4B Q07343 2/20 0.34
PDE4C Q08493 2/20 0.34
PDE4D Q08499 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17965689 1.00 CSNK2A2 (0.36) CSNK2A2CSNK2BCSNK2A1PDE4APDE4B
SCHEMBL29697534 0.79 KMT2A (0.45) CSNK2A2CSNK2BCSNK2A1
SCHEMBL24489348 0.76 CSNK2A2 (0.41) CSNK2A2CSNK2BCSNK2A1PDE4APDE4B
SCHEMBL23027286 0.76 CSNK2A2 (0.41) CSNK2A2CSNK2BCSNK2A1PDE4APDE4B
SCHEMBL23027307 0.76 CSNK2A2 (0.61) CSNK2A2CSNK2BCSNK2A1PDE4APDE4B
SCHEMBL27240658 0.73 KMT2A (0.35) CSNK2A2CSNK2BCSNK2A1
SCHEMBL8330397 0.71 LMNA (0.51)
SCHEMBL316573 0.71 LMNA (0.51)
SCHEMBL31554263 0.71 CSNK2A2 (0.31) CSNK2A2CSNK2BCSNK2A1
SCHEMBL24489465 0.70 CSNK2A2 (0.32) CSNK2A2CSNK2BCSNK2A1PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115557900-B Synthesis method of 3-substituted pyridazine derivative 常州大学 2024-03-15 CN claimed
CN-116789594-A Synthesis method of N-alkylated pyridine-2-ketone derivative 常州大学 2023-09-22 CN claimed
CN-116768777-A Method for constructing nitrogen-nitrogen axis chiral dipyrrole compound with high stereoselectivity 常州大学 2023-09-19 CN claimed
CN-114605302-B Method for synthesizing carbon-carbon axis chiral indole-naphthol biaryl compound by using chiral rhodium catalysis 常州大学 2023-07-25 CN claimed
CN-115557900-A Synthetic method of 3-substituted pyridazine derivative 常州大学 2023-01-03 CN claimed
CN-114605302-A Method for synthesizing carbon-carbon axis chiral indole-naphthol biaryl compound by using chiral rhodium as catalyst 常州大学 2022-06-10 CN claimed
CN-114560802-A Method for constructing carbon-nitrogen axis chiral indole-naphthol biaryl compound 常州大学 2022-05-31 CN claimed
CN-115557900-B Synthesis method of 3-substituted pyridazine derivative 常州大学 2024-03-15 CN disclosed
CN-115707518-B Chiral binuclear rhodium metal catalyst and preparation method and application thereof 华南理工大学 2023-12-19 CN disclosed
CN-116789594-A Synthesis method of N-alkylated pyridine-2-ketone derivative 常州大学 2023-09-22 CN disclosed
CN-116768777-A Method for constructing nitrogen-nitrogen axis chiral dipyrrole compound with high stereoselectivity 常州大学 2023-09-19 CN disclosed
CN-113896662-B Amino cyclopropane carboxylic acid compound and preparation method and application thereof 五邑大学 2023-08-29 CN disclosed
CN-113248480-B Method for chemically and enantioselectively inserting N-H bond of 2-pyridone or 3-pyridazinone into furan carbene 常州大学 2023-08-22 CN disclosed
CN-114560802-B Method for constructing carbon-nitrogen axis chiral indole-naphthol biaryl compound 常州大学 2023-08-22 CN disclosed
CN-114605302-B Method for synthesizing carbon-carbon axis chiral indole-naphthol biaryl compound by using chiral rhodium catalysis 常州大学 2023-07-25 CN disclosed
CN-115707518-A Chiral binuclear rhodium metal catalyst and preparation method and application thereof 华南理工大学 2023-02-21 CN disclosed
CN-115557900-A Synthetic method of 3-substituted pyridazine derivative 常州大学 2023-01-03 CN disclosed
CN-114605302-A Method for synthesizing carbon-carbon axis chiral indole-naphthol biaryl compound by using chiral rhodium as catalyst 常州大学 2022-06-10 CN disclosed
CN-114560802-A Method for constructing carbon-nitrogen axis chiral indole-naphthol biaryl compound 常州大学 2022-05-31 CN disclosed