Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316573 | 1.00 | LMNA (0.51) | LMNAALDH1A1GAATP53POLB | |
| SCHEMBL30353214 | 0.98 | LMNA (0.50) | LMNAALDH1A1GAATP53POLB | |
| SCHEMBL11816701 | 0.86 | LMNA (0.49) | LMNAALDH1A1GAATP53POLB | |
| SCHEMBL30353246 | 0.84 | KDM4E (0.56) | LMNAALDH1A1GAAKDM4ECYP3A4 | |
| SCHEMBL411858 | 0.83 | LMNA (0.46) | LMNAALDH1A1GAATP53POLB | |
| SCHEMBL317136 | 0.82 | MEN1 (0.53) | POLBCYP2D6TDP1 | |
| SCHEMBL411712 | 0.81 | LMNA (0.48) | LMNAALDH1A1GAATP53POLB | |
| SCHEMBL25667517 | 0.80 | LMNA (0.43) | LMNAALDH1A1GAATP53POLB | |
| SCHEMBL27240658 | 0.80 | KMT2A (0.35) | LMNAALDH1A1GAATP53KDM4E | |
| SCHEMBL26931875 | 0.80 | LMNA (0.47) | LMNAALDH1A1GAATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462636-A | Synthesis method of 3-alkyl quinoxaline-2 (1H) ketone compound mediated by visible light | 河南师范大学 | 2023-07-21 | — | — | CN | disclosed |
| US-11512071-B2 | Decarboxylative cross-coupling and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2022-11-29 | — | — | US | disclosed |
| CN-111315829-B | Small molecule organic dye | 巴塞尔大学 | 2022-11-04 | — | — | CN | disclosed |
| US-11214687-B2 | Small-molecule organic dyes | UNIVERSITÄT BASEL (CH) | 2022-01-04 | — | — | US | disclosed |
| US-20200255667-A1 | SMALL-MOLECULE ORGANIC DYES | UNIVERSITÄT BASEL (CH) | 2020-08-13 | — | — | US | disclosed |
| CN-111315829-A | Small molecule organic dye | 巴塞尔大学 | 2020-06-19 | — | — | CN | disclosed |
| US-20200148668-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2020-05-14 | — | — | US | disclosed |
| US-10538509-B2 | Decarboxylative cross-coupling and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-01-21 | — | — | US | disclosed |
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
| EP-1553937-B1 | GLYCINENITRILE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | BRISTOL MYERS SQUIBB CO (US) | 2010-06-02 | — | — | EP | disclosed |
| WO-2004037181-A2 | GLYCINENITRILE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | PPOX, DDO, DDC | LMNA 4743/4885ALDH1A1 149/4885GAA 2338/4885 |
| US-11512071-B2 | Decarboxylative cross-coupling and applications thereof | PPOX, DDO, DDC | LMNA 4743/4885ALDH1A1 149/4885GAA 2338/4885 |
| US-10538509-B2 | Decarboxylative cross-coupling and applications thereof | PPOX, DDC, DDO | LMNA 4676/4885ALDH1A1 130/4885GAA 2310/4885 |
| US-11214687-B2 | Small-molecule organic dyes | SLC7A5, SLC30A5, ZKSCAN2 | LMNA 4718/4885ALDH1A1 2000/4885GAA 4401/4885 |
| US-20200255667-A1 | SMALL-MOLECULE ORGANIC DYES | SLC7A5, SLC30A5, ZKSCAN2 | LMNA 4718/4885ALDH1A1 2000/4885GAA 4401/4885 |
| US-20200148668-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | PPOX, DDO, DDC | LMNA 4743/4885ALDH1A1 149/4885GAA 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.