Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316573 | 0.80 | LMNA (0.51) | LMNAHTTKDM4EL3MBTL1DNMT1 | |
| SCHEMBL8330397 | 0.80 | LMNA (0.51) | LMNAHTTKDM4EL3MBTL1DNMT1 | |
| SCHEMBL31554263 | 0.79 | CSNK2A2 (0.31) | DNMT1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30353214 | 0.79 | LMNA (0.50) | LMNAHTTKDM4EL3MBTL1DNMT1 | |
| SCHEMBL17965689 | 0.73 | CSNK2A2 (0.36) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29697534 | 0.73 | KMT2A (0.45) | KMT2ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29697484 | 0.73 | CSNK2A2 (0.36) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30353246 | 0.70 | KDM4E (0.56) | KMT2ALMNAMAPTHTTKDM4E | |
| SCHEMBL11816701 | 0.68 | LMNA (0.49) | KMT2ALMNAHTTKDM4EL3MBTL1 | |
| SCHEMBL317136 | 0.68 | MEN1 (0.53) | KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190804-A1 | Diruthenium Catalyst Compositions and Synthetic Processes Related Thereto | UNIV EMORY (US) | 2024-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190804-A1 | Diruthenium Catalyst Compositions and Synthetic Processes Related Thereto | DAO, SCO2, IDH2 | KMT2A 1478/4885LMNA 4710/4885SMN1; SMN2 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.