SCHEMBL2969754

SCHEMBL2969754

CNC(=O)CN(CC1CCN(Cc2cccc(OC(F)(F)F)c2)CC1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHRM4 P08173 10/20 0.54
CHRM2 P08172 4/20 0.51
CHRM1 P11229 3/20 0.51
CARM1 Q86X55 1/20 0.47
PRMT6 Q96LA8 1/20 0.47
CHRM3 P20309 1/20 0.47
CXCR3 P49682 1/20 0.46
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
OPRM1 P35372 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2973384 0.89 BCHE (0.52) CHRM4CHRM2CHRM1
SCHEMBL2983168 0.86 CCR8 (0.52) CHRM4
SCHEMBL2979082 0.85 CCR8 (0.48)
SCHEMBL2972278 0.82 SIGMAR1 (0.55)
SCHEMBL3583996 0.78 CHRM4 (0.68) CHRM4CHRM2CHRM1CHRM3OPRM1
SCHEMBL3583999 0.78 CHRM4 (0.53) CHRM4CHRM2CHRM1CHRM3CXCR3
SCHEMBL2982162 0.78 POLB (0.52)
SCHEMBL2975693 0.78 CHRM4 (0.60) CHRM4CHRM2CHRM1CHRM3
SCHEMBL28759676 0.78 CHRM4 (0.56) CHRM4CHRM2CHRM1CARM1PRMT6
SCHEMBL2970167 0.78 SIGMAR1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781590-B2 Piperidinylalkylcarbamate derivatives, methods for their preparation and the therapeutic use thereof as fatty acid amido hydrolase enzyme inhibitors SANOFI-AVENTIS (FR) 2010-08-24 US disclosed
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS SANOFI-AVENTIS (FR) 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS FAAH, FAAH2, CNR2 CHRM4 2788/4885CHRM2 3665/4885CHRM1 3552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.