Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267091 | 1.00 | SLC6A3 (0.35) | SLC6A3TP53NOS2KDM4EGMNN | |
| SCHEMBL21794157 | 0.93 | — | — | |
| SCHEMBL1864816 | 0.93 | — | — | |
| Tetrahydrofuran SCHEMBL7251789 | 0.90 | NOS2 (0.32) | NOS2LMNA | |
| SCHEMBL11155080 | 0.85 | SLC6A3 (0.33) | SLC6A3 | |
| SCHEMBL7146210 | 0.83 | SLC6A3 (0.33) | SLC6A3TP53 | |
| SCHEMBL28292900 | 0.83 | SLC6A3 (0.36) | SLC6A3TP53 | |
| SCHEMBL26926290 | 0.82 | SLC6A3 (0.31) | SLC6A3 | |
| SCHEMBL4444063 | 0.81 | SLC6A3 (0.33) | SLC6A3 | |
| SCHEMBL6972225 | 0.79 | SLC6A3 (0.32) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957357-A | Aminoglycoside derivatives and their use in the treatment of genetic disorders | ELOXX制药有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-108350014-B | Aminoglycoside derivatives and their use in the treatment of genetic disorders | ELOXX制药有限公司 | 2022-06-10 | — | — | CN | disclosed |