Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870865 | 0.94 | GAA (0.32) | — | |
| SCHEMBL1859978 | 0.82 | L3MBTL1 (0.37) | — | |
| SCHEMBL2267091 | 0.81 | SLC6A3 (0.35) | SLC6A3 | |
| SCHEMBL29697553 | 0.81 | SLC6A3 (0.35) | SLC6A3 | |
| SCHEMBL7157902 | 0.81 | L3MBTL1 (0.41) | — | |
| SCHEMBL15604555 | 0.75 | NOS2 (0.36) | SLC6A3 | |
| SCHEMBL6955217 | 0.75 | LMNA (0.42) | — | |
| SCHEMBL11780841 | 0.75 | SLC6A3 (0.37) | SLC6A3 | |
| SCHEMBL5971741 | 0.75 | SLC6A3 (0.37) | SLC6A3 | |
| SCHEMBL21794157 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136620-A2 | METHODS AND COMPOSITIONS FOR TARGETING AFAP | West Virginia University C/o Office Of Technology (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008133789-A2 | METHODS AND COMPOSITIONS FOR TARGETING AFAP | WEST VIRGINIA UNIVERSITY C/O OFFICE OF TECHNOLGOY TRANSFER WEST VIRGINIA RESEARCH CORPORATION (US) | 2008-11-06 | — | — | WO | disclosed |
| US-20080234232-A1 | Methods and compositions for targeting AFAP | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234232-A1 | Methods and compositions for targeting AFAP | ARPC5, ARPC2, ACTR2 | SLC6A3 4771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.