Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | RGS12 | O14924 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296982 | 1.00 | USP2 (0.53) | USP2ALOX15HSD17B10KDM4EHIF1A | |
| SCHEMBL29141540 | 0.92 | USP2 (0.46) | USP2ALOX15HSD17B10KDM4EHIF1A | |
| SCHEMBL9847981 | 0.89 | USP2 (0.50) | USP2ALOX15HSD17B10KDM4EHIF1A | |
| SCHEMBL9851430 | 0.87 | USP2 (0.45) | USP2ALOX15HSD17B10KDM4EHIF1A | |
| SCHEMBL5672308 | 0.87 | USP2 (0.50) | USP2ALOX15HSD17B10KDM4EHIF1A | |
| SCHEMBL5672304 | 0.87 | USP2 (0.50) | USP2ALOX15HSD17B10KDM4EHIF1A | |
| SCHEMBL28551296 | 0.87 | USP2 (0.50) | USP2ALOX15HSD17B10KDM4EHIF1A | |
| SCHEMBL20722991 | 0.84 | USP2 (0.47) | USP2ALOX15HSD17B10KDM4EHIF1A | |
| SCHEMBL20722707 | 0.84 | USP2 (0.47) | USP2ALOX15HSD17B10KDM4EHIF1A | |
| Hydrochloric Acid SCHEMBL20722737 | 0.82 | USP2 (0.46) | USP2ALOX15HSD17B10KDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025949-A1 | Beta-Arrestin Effectors and Compositions and Methods of Use Thereof | TREVENA, INC. | 2024-01-25 | — | — | US | claimed |
| WO-2021216529-A1 | β-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | TREVENA, INC. (US) | 2021-10-28 | — | — | WO | claimed |
| US-20210324005-A1 | Beta-Arrestin Effectors and Compositions and Methods of Use Thereof | TREVENA, INC. | 2021-10-21 | — | — | US | claimed |
| US-20180016301-A1 | Synthesis of Beta-Arrestin Effectors | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2018-01-18 | — | — | US | claimed |
| EP-3145524-A2 | SYNTHESIS OF BETA-ARRESTIN EFFECTORS | Trevena, Inc. (US) | 2017-03-29 | — | — | EP | claimed |
| EP-2376101-B1 | BETA-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | TREVENA INC (US) | 2015-12-02 | — | — | EP | claimed |
| WO-2015179349-A2 | SYNTHESIS OF BETA-ARRESTIN EFFECTORS | TREVENA, INC. (US) | 2015-11-26 | — | — | WO | claimed |
| US-20150329593-A1 | Synthesis of Beta-Arrestin Effectors | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2015-11-19 | — | — | US | claimed |
| US-20150166604-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | TREVENA, INC. | 2015-06-18 | — | — | US | claimed |
| US-8993511-B2 | β-arrestin effectors and compositions and methods of use thereof | TREVENA, INC. (US) | 2015-03-31 | — | — | US | claimed |
| US-20140357562-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | TREVENA, INC. | 2014-12-04 | — | — | US | claimed |
| US-20140336123-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | TREVENA, INC. | 2014-11-13 | — | — | US | claimed |
| US-8809260-B2 | β-arrestin effectors and compositions and methods of use thereof | TREVENA, INC. (US) | 2014-08-19 | — | — | US | claimed |
| US-20130274176-A1 | BETA-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | TREVENA, INC. (US) | 2013-10-17 | — | — | US | claimed |
| EP-2376101-A2 | ß-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | Trevena, Inc. (US) | 2011-10-19 | — | — | EP | claimed |
| US-20100184701-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | TREVENA, INC. | 2010-07-22 | — | — | US | claimed |
| WO-2010077339-A2 | β-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | TREVENA, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| EP-4667483-A1 | HUMAN TRANSFERRIN RECEPTOR-BINDING PEPTIDE | JCR Pharmaceuticals Co., Ltd. (JP) | 2025-12-24 | — | — | EP | disclosed |
| WO-2007065808-A2 | NEUROPEPTIDE-2 RECEPTOR-AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-06-14 | — | — | WO | disclosed |
| US-20070135351-A1 | Neuropeptide-2 receptor (Y-2R) agonists and uses thereof | CONDE-KNAPE KARIN | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016301-A1 | Synthesis of Beta-Arrestin Effectors | ARRB1, ADRB1, ADRB3 | USP2 1580/4885ALOX15 4560/4885HSD17B10 2629/4885 |
| US-20070135351-A1 | Neuropeptide-2 receptor (Y-2R) agonists and uses thereof | NPY2R, NPY1R, NPY4R | USP2 2739/4885ALOX15 1425/4885HSD17B10 1955/4885 |
| US-20150329593-A1 | Synthesis of Beta-Arrestin Effectors | ARRB1, ADRB1, ADRB3 | USP2 1580/4885ALOX15 4560/4885HSD17B10 2629/4885 |
| US-20140336123-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | ARRB1, ADRB1, ADRB3 | USP2 1527/4885ALOX15 3979/4885HSD17B10 2466/4885 |
| US-20150166604-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | ARRB1, ADRB1, ADRB3 | USP2 1527/4885ALOX15 3979/4885HSD17B10 2466/4885 |
| US-20210324005-A1 | Beta-Arrestin Effectors and Compositions and Methods of Use Thereof | ARRB1, ADRB1, FGB | USP2 2028/4885ALOX15 3634/4885HSD17B10 3693/4885 |
| US-20130274176-A1 | BETA-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | ARRB1, ADRB1, ADRB3 | USP2 1527/4885ALOX15 3979/4885HSD17B10 2466/4885 |
| US-20140357562-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | ARRB1, ADRB1, ADRB3 | USP2 1527/4885ALOX15 3979/4885HSD17B10 2466/4885 |
| US-20240025949-A1 | Beta-Arrestin Effectors and Compositions and Methods of Use Thereof | ARRB1, FGB, SARS1 | USP2 2017/4885ALOX15 3659/4885HSD17B10 3697/4885 |
| US-20100184701-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | ARRB1, ADRB1, ADRB3 | USP2 1527/4885ALOX15 3979/4885HSD17B10 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.