Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.51 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463602 | 0.83 | PDE3B (0.57) | GPR119PDE3BPDE3APDE4APDE4B | |
| SCHEMBL10463603 | 0.83 | PDE3B (0.68) | GPR119PDE3BPDE3A | |
| SCHEMBL2590656 | 0.82 | GPR119 (0.77) | GPR119 | |
| Hydrochloric Acid SCHEMBL9781443 | 0.81 | PDE3B (0.56) | GPR119PDE3BPDE3APDE4APDE4B | |
| Hydrochloric Acid SCHEMBL9781446 | 0.81 | PDE3B (0.66) | GPR119PDE3BPDE3A | |
| SCHEMBL7294564 | 0.79 | GPR119 (0.61) | GPR119PDE3BPDE3APDE4APDE4B | |
| SCHEMBL7952005 | 0.74 | KDM4E (0.68) | — | |
| SCHEMBL14063447 | 0.72 | KDM4E (0.66) | — | |
| SCHEMBL10353457 | 0.72 | PDE3B (0.71) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL16157195 | 0.72 | PDE3B (0.68) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605388-B | Stimulus-responsive nitrogen heterocyclic compound, and preparation method and application thereof | 广东南华工商职业学院 | 2024-05-03 | — | — | CN | disclosed |
| CN-114605388-A | Stimulus-response type nitrogen heterocyclic compound and preparation method and application thereof | 广东南华工商职业学院 | 2022-06-10 | — | — | CN | disclosed |