SCHEMBL296991

SCHEMBL296991

O=C(NO)c1ccc([N+](=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.68
KMT2A Q03164 3/20 0.68
POLB P06746 2/20 0.68
CES1 P23141 1/20 0.63
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
TDP1 Q9NUW8 1/20 0.61
TSHR P16473 1/20 0.59
ALDH1A1 P00352 1/20 0.59
MAPK1 P28482 1/20 0.59
MAPT P10636 3/20 0.57
FLT1 P17948 1/20 0.57
FLT4 P35916 1/20 0.57
KDR P35968 1/20 0.57
HDAC3 O15379 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC10 Q969S8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674700 0.89 KMT2A (0.73) MEN1KMT2APOLBALDH1A1MAPK1
SCHEMBL28612321 0.88 MEN1 (0.74) MEN1KMT2APOLBCA1CA2
Trifluoromethanesulfonic Acid SCHEMBL31279314 0.85 POLB (0.53) MEN1KMT2APOLBCES1CA1
SCHEMBL27815181 0.85 MAPT (0.67) MEN1KMT2APOLBCES1CA1
SCHEMBL28723007 0.85 MEN1 (0.82) MEN1KMT2APOLBCES1CA1
SCHEMBL15480653 0.83 ATM (0.52) MEN1KMT2APOLBALDH1A1MAPK1
SCHEMBL14288331 0.83 HDAC1 (0.64) MEN1KMT2ACA1CA2TDP1
SCHEMBL9848997 0.82 ALDH1A1 (0.62) MEN1KMT2APOLBCES1CA1
Potassium Ion SCHEMBL10903588 0.82 CES1 (0.61) MEN1KMT2APOLBCES1CA1
SCHEMBL6973230 0.82 CES1 (0.61) MEN1KMT2APOLBCES1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119176819-B Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase 山东第二医科大学 2025-02-14 CN claimed
CN-119176819-A Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase 山东第二医科大学 2024-12-24 CN claimed
US-20240319601-A1 METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2024-09-26 US claimed
US-11981648-B2 Method for the synthesis of 3-R-1,4,2-dioxazol-5-ones TESLA, INC. (US) 2024-05-14 US claimed
CN-117597628-A Method for forming pattern 三星SDI株式会社 2024-02-23 CN claimed
US-20240019784-A1 METAL CONTAINING PHOTORESIST DEVELOPER COMPOSITION, AND METHOD OF FORMING PATTERNS INCLUDING STEP OF DEVELOPING USING THE COMPOSITION SAMSUNG SDI CO., LTD. (KR) 2024-01-18 US claimed
CN-117348341-A Metal-containing photoresist developer composition and pattern forming method 三星SDI株式会社 2024-01-05 CN claimed
US-20230029852-A1 METHOD FOR THE SYNTHESIS OF 3-R-1,4,2-DIOXAZOL-5-ONES PANASONIC HOLDINGS CORPORATION (JP) 2023-02-02 US claimed
CN-110003134-B Chiral camphor sulfonyl hydrazide derived catalyst, preparation method and application thereof 上海工程技术大学 2022-08-26 CN claimed
WO-2026046899-A1 PYRAZOLO[5,1-f][1,2,4]TRIAZIN-4-ONES AS INHIBITORS OF NOX4 BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2026-03-05 WO disclosed
CN-120157555-A Preparation method of primary amide compound 浙江工业大学 2025-06-17 CN disclosed
CN-119176819-B Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase 山东第二医科大学 2025-02-14 CN disclosed
CN-119176819-A Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase 山东第二医科大学 2024-12-24 CN disclosed
US-20240319601-A1 METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2024-09-26 US disclosed
WO-2004069947-A1 METHOD OF POLISHING A SILICON-CONTAINING DIELECTRIC CABOT MICROELECTRONICS CORPORATION (US) 2004-08-19 WO disclosed
US-20040152309-A1 Method of polishing a silicon-containing dielectric CABOT MICROELECTRONICS CORPORATION 2004-08-05 US disclosed
CN-1073571-C Dialkyl tin compound of mononuclear aromatic heterocycle hydroxamate and its synthesis UNIV SHANXI (CN) 2001-10-24 CN disclosed
CN-1073566-C Binuclear aromatic, heterocyclic monoacyl hydroxamic acid dialkyl-tin compounds, and method for synthesizing same UNIV SHANXI (CN) 2001-10-24 CN disclosed
CN-1242369-A Binuclear aromatic, heterocyclic monoacyl hydroxamic acid dialkyl-tin compounds, and method for synthesizing same UNIV SHANXI (CN) 2000-01-26 CN disclosed
US-3978208-A ACETOHYDROXAMIC ACID EISAI CO., LTD. (JA) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11981648-B2 Method for the synthesis of 3-R-1,4,2-dioxazol-5-ones CYP4X1, DDO, CYP4B1 MEN1 1474/4885KMT2A 1995/4885POLB 1124/4885
US-20230029852-A1 METHOD FOR THE SYNTHESIS OF 3-R-1,4,2-DIOXAZOL-5-ONES CYP4X1, DDO, CYP4B1 MEN1 1474/4885KMT2A 1995/4885POLB 1124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.