Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815181 | 0.83 | MAPT (0.67) | CES1MEN1KMT2APOLBCA1 | |
| SCHEMBL28723007 | 0.83 | MEN1 (0.82) | CES1MEN1KMT2APOLBCA1 | |
| SCHEMBL296991 | 0.82 | MEN1 (0.68) | CES1MEN1KMT2APOLBCA1 | |
| SCHEMBL9848997 | 0.80 | ALDH1A1 (0.62) | CES1MEN1KMT2APOLBCA1 | |
| SCHEMBL8866584 | 0.80 | CES1 (0.61) | CES1MEN1KMT2APOLBCA1 | |
| SCHEMBL165760 | 0.80 | TSHR (0.62) | CES1MEN1KMT2APOLBCA1 | |
| Potassium Ion SCHEMBL10903588 | 0.80 | CES1 (0.61) | CES1MEN1KMT2APOLBCA1 | |
| SCHEMBL223451 | 0.80 | MAPT (0.63) | CES1MEN1KMT2APOLBCA1 | |
| SCHEMBL6465643 | 0.80 | CES1 (0.61) | CES1MEN1KMT2APOLBCA1 | |
| SCHEMBL1524805 | 0.79 | MAPT (0.62) | CES1MEN1KMT2APOLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |