Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2372239 | 1.00 | DRD2 (0.46) | DRD2HSD17B10DRD3 | |
| SCHEMBL2372244 | 1.00 | DRD2 (0.46) | DRD2HSD17B10DRD3 | |
| Trifluoroacetic Acid SCHEMBL2073793 | 0.80 | DRD2 (0.46) | DRD2HSD17B10DRD3 | |
| SCHEMBL2075262 | 0.79 | DRD2 (0.50) | DRD2HSD17B10DRD3 | |
| SCHEMBL11773840 | 0.79 | DRD2 (0.53) | DRD2DRD3 | |
| SCHEMBL29699382 | 0.73 | ADRB1 (0.36) | — | |
| SCHEMBL2372856 | 0.73 | ADRB1 (0.36) | — | |
| SCHEMBL2372852 | 0.73 | ADRB1 (0.36) | — | |
| SCHEMBL14784270 | 0.71 | CFTR (0.42) | — | |
| SCHEMBL11732086 | 0.71 | DRD2 (0.53) | DRD2HSD17B10DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980121-A1 | PYRIDINE AND PYRAZINE DERIVATIVE FOR THE TREATMENT OF CF, COPD, AND BRONCHIECTASIS | Novartis AG (CH) | 2022-04-13 | — | — | EP | disclosed |