SCHEMBL29699328

SCHEMBL29699328

CCC(C)C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O

nearest known ligand 0.86

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NAA50 Q9GZZ1 2/20 0.86
CHAT P28329 2/20 0.82
EP300 Q09472 3/20 0.81
AURKA O14965 2/20 0.81
KAT5 Q92993 2/20 0.81
KAT2B Q92831 1/20 0.81
CREBBP Q92793 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22612561 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT5
SCHEMBL120171 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT5
SCHEMBL26135395 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT5
SCHEMBL1533824 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT5
SCHEMBL30411982 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT5
SCHEMBL22609304 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT5
SCHEMBL2935253 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT5
SCHEMBL22612510 1.00 NAA50 (0.86) NAA50CHATEP300AURKAKAT5
SCHEMBL28487648 0.98 NAA50 (0.84) NAA50CHATEP300AURKAKAT5
SCHEMBL30046331 0.96 NAA50 (0.84) NAA50CHATEP300AURKAKAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151709-A1 COMPOSITIONS FOR INDUCING OR RESCUING GLYCOLYSIS AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-07-18 WO claimed
US-20230058160-A1 METABOLITE-BASED POLYMERS, MICROPARTICLES, AND NANOPARTICLES FOR IMMUNOTHERAPY AND METHODS OF TREATING A DISEASE OR DISORDER ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2023-02-23 US claimed
EP-3731859-B1 PYRIDAZINE COMPOUNDS FOR USE TO TREAT DISORDERS ASSOCIATED WITH CASTOR ST JUDE CHILDRENS RES HOSPITAL INC (US) 2025-08-20 EP disclosed
EP-4499817-A1 BIOSYNTHESIS Plant Bioscience Limited (GB) 2025-02-05 EP disclosed
CN-118742650-A Production of saponins in yeast 加利福尼亚大学董事会 2024-10-01 CN disclosed
WO-2024151709-A1 COMPOSITIONS FOR INDUCING OR RESCUING GLYCOLYSIS AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-07-18 WO disclosed
CN-118147102-A Polypeptide for improving avermectin B1a yield and application thereof 中国农业大学 2024-06-07 CN disclosed
CN-118147102-A Polypeptide for improving avermectin B1a yield and application thereof 中国农业大学 2024-06-07 CN disclosed
EP-4298217-A1 TISSUE-SPECIFIC METHODS AND COMPOSITIONS FOR MODULATING A GENOME Flagship Pioneering Innovations VI, LLC (US) 2024-01-03 EP disclosed
EP-4262814-A1 METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR St. Jude Children's Research Hospital, Inc. (US) 2023-10-25 EP disclosed
WO-2023180677-A1 Biosynthesis PLANT BIOSCIENCE LIMITED (GB) 2023-09-28 WO disclosed
CN-116426454-A Genetic engineering method for improving titer and proportion of avermectin B1a component 浙江工业大学 2023-07-14 CN disclosed
CN-115725665-A Hyperforin biosynthesis gene cluster and application thereof 中国科学院分子植物科学卓越创新中心 2023-03-03 CN disclosed
US-20230058160-A1 METABOLITE-BASED POLYMERS, MICROPARTICLES, AND NANOPARTICLES FOR IMMUNOTHERAPY AND METHODS OF TREATING A DISEASE OR DISORDER ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2023-02-23 US disclosed
EP-4065556-A1 MACROCYCLIC PANTETHEINE DERIVATIVES AND USES THEREOF Comet Therapeutics, Inc. (US) 2022-10-05 EP disclosed
WO-2022183210-A1 TISSUE-SPECIFIC METHODS AND COMPOSITIONS FOR MODULATING A GENOME FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2022-09-01 WO disclosed
WO-2022133034-A1 METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2022-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230058160-A1 METABOLITE-BASED POLYMERS, MICROPARTICLES, AND NANOPARTICLES FOR IMMUNOTHERAPY AND METHODS OF TREATING A DISEASE OR DISORDER PC, CD47, CD14 NAA50 3009/4885CHAT 2224/4885EP300 2912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.