Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | APEX1 | P27695 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | RGS12 | O14924 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347877 | 1.00 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL30027889 | 0.88 | GAA (0.79) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL31040284 | 0.88 | GAA (0.79) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL8736645 | 0.86 | GAA (0.76) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL18255551 | 0.86 | GAA (0.75) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL30388881 | 0.86 | GAA (0.75) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL8792 | 0.86 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL10535396 | 0.86 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL30337229 | 0.86 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL153055 | 0.85 | GAA (0.74) | GAATSHRNFKB1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133738-A1 | BIOMARKER FOR PREOPERATIVE IDENTIFICATION OF BENIGN AND MALIGNANT THYROID NODULES, AND KIT AND APPLICATION THEREOF | 中山大学附属第一医院 | 2022-06-30 | — | — | WO | claimed |