Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 0.75 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | APEX1 | P27695 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | RGS12 | O14924 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29699330 | 1.00 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL30027889 | 0.88 | GAA (0.79) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL31040284 | 0.88 | GAA (0.79) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL8736645 | 0.86 | GAA (0.76) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL18255551 | 0.86 | GAA (0.75) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL30388881 | 0.86 | GAA (0.75) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL8792 | 0.86 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL10535396 | 0.86 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| Homovanillic Acid SCHEMBL30337229 | 0.86 | GAA (1.00) | GAATSHRNFKB1TDP1ALDH1A1 | |
| SCHEMBL153055 | 0.85 | GAA (0.74) | GAATSHRNFKB1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 526 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024194018-A1 | METHOD FOR PRODUCING CORYTUBERINE AND SALUTARIDINE | Universität Graz (AT) | 2024-09-26 | — | — | WO | claimed |
| EP-4431612-A1 | PROCESS FOR THE PREPARATION OF CORORYLOURIN AND SALUTARIDINE | Universität Graz (AT) | 2024-09-18 | — | — | EP | claimed |
| CN-109942593-B | Total synthesis method of racemic tetrandrine | 浙江金华康恩贝生物制药有限公司 | 2021-08-27 | — | — | CN | claimed |
| US-20210002226-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ALTER DOMUS (US) LLC | 2021-01-07 | — | — | US | claimed |
| CN-110791003-A | Crosslinked polyethylene cable insulating material and preparation method thereof | 宋晓明 | 2020-02-14 | — | — | CN | claimed |
| CN-109942593-A | A kind of total synthesis method of racemization hanfangchin A | 浙江金华康恩贝生物制药有限公司 | 2019-06-28 | — | — | CN | claimed |
| US-20190085007-A1 | 4-methylcatechol Derivatives and Uses Thereof | Thanares GmbH (DE) | 2019-03-21 | — | — | US | claimed |
| WO-2018191472-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | KEMPHARM, INC. (US) | 2018-10-18 | — | — | WO | claimed |
| US-20170312270-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2017-11-02 | — | — | US | claimed |
| EP-3226907-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS AND MAKING AND USE THEREOF | Kempharm, Inc. (US) | 2017-10-11 | — | — | EP | claimed |
| US-20120142720-A1 | Phenylethanoic Acid, Phenylpropanoic Acid and Phenylpropenoic Acid Conjugates and Prodrugs of Hydrocodone, Methods of Making and Use Thereof | KEMPHARM, INC. (US) | 2012-06-07 | — | — | US | claimed |
| EP-2448408-A1 | PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHODS OF MAKING AND USE THEREOF | Kempharm, Inc. (US) | 2012-05-09 | — | — | EP | claimed |
| US-20120016390-A1 | BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE | KNC NER ACQUISITION SUB, INC. (US) | 2012-01-19 | — | — | US | claimed |
| WO-2012009664-A2 | BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE | KNC NER ACQUISITION SUB, INC. (US) | 2012-01-19 | — | — | WO | claimed |
| WO-2011002995-A1 | PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHODS OF MAKING AND USE THEREOF | KEMPHARM, INC. (US) | 2011-01-06 | — | — | WO | claimed |
| US-20110002991-A1 | PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHOD OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2011-01-06 | — | — | US | claimed |
| CN-1045442-C | Levo- and dextro-rotary chloroscouriline (tetrahydroprotoberberines) and application thereof | SHANGHAI INST OF MEDICINE CHIN (CN) | 1999-10-06 | — | — | CN | claimed |
| CN-1115318-A | Levo- and dextro-rotary chloroscouriline (tetrahydroprotoberberines) and application thereof | SHANGHAI INST MATERIA MEDICA (CN) | 1996-01-24 | — | — | CN | claimed |
| WO-1990009976-A1 | METHOD OF SYNTHESIS OF HYDROXY-SUBSTITUTED-4-ALKOXYPHENYLACETIC ACIDS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1990-09-07 | — | — | WO | claimed |
| US-4025553-A | Production of o-hydroxybenzyl alcohols | SHIONOGI & CO., LTD. (JA) | 1977-05-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142720-A1 | Phenylethanoic Acid, Phenylpropanoic Acid and Phenylpropenoic Acid Conjugates and Prodrugs of Hydrocodone, Methods of Making and Use Thereof | CYP7A1, CYP2B6, CYP2D6 | GAA 1112/4885TSHR 3473/4885NFKB1 2239/4885 |
| US-20170312270-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, OPRD1 | GAA 2640/4885TSHR 1155/4885NFKB1 437/4885 |
| US-20190085007-A1 | 4-methylcatechol Derivatives and Uses Thereof | ST3GAL3, GALE, DPP4 | GAA 330/4885TSHR 4840/4885NFKB1 2505/4885 |
| US-20110002991-A1 | PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHOD OF MAKING AND USE THEREOF | CYP7A1, CYP2B6, CYP2D6 | GAA 1146/4885TSHR 3482/4885NFKB1 2203/4885 |
| US-20210002226-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | OPRM1, OPRK1, OPRD1 | GAA 2449/4885TSHR 349/4885NFKB1 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.