Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24938208 | 0.86 | L3MBTL1 (0.84) | L3MBTL1HRH3ACHEGAASMN1; SMN2 | |
| SCHEMBL596252 | 0.86 | L3MBTL1 (0.96) | L3MBTL1HRH3ACHEGAASMN1; SMN2 | |
| SCHEMBL27790681 | 0.84 | L3MBTL1 (0.76) | L3MBTL1HRH3ACHEFAAHHDAC1 | |
| SCHEMBL610772 | 0.84 | L3MBTL1 (1.00) | L3MBTL1HRH3ACHEGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27853152 | 0.84 | L3MBTL1 (0.93) | L3MBTL1HRH3ACHEGAASMN1; SMN2 | |
| SCHEMBL1626076 | 0.84 | L3MBTL1 (1.00) | L3MBTL1HRH3ACHEGAASMN1; SMN2 | |
| SCHEMBL7269112 | 0.84 | L3MBTL1 (1.00) | L3MBTL1HRH3ACHEGAASMN1; SMN2 | |
| SCHEMBL9212361 | 0.84 | L3MBTL1 (1.00) | L3MBTL1HRH3ACHEGAASMN1; SMN2 | |
| SCHEMBL8903528 | 0.83 | L3MBTL1 (0.97) | L3MBTL1HRH3ACHEGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL12494696 | 0.83 | L3MBTL1 (0.97) | L3MBTL1HRH3ACHEGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230089374-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2023-03-23 | — | — | US | disclosed |
| US-20230088214-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2023-03-23 | — | — | US | disclosed |
| US-20230079913-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2023-03-16 | — | — | US | disclosed |
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | BIOMARIN PHARMACEUTICAL INC. (US) | 2022-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230079913-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | XDH, PNPO, AGXT | L3MBTL1 1830/4885HRH3 3323/4885HCRTR1 1657/4885 |
| US-20230088214-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | XDH, PNPO, AGXT | L3MBTL1 1685/4885HRH3 3415/4885HCRTR1 1549/4885 |
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | XDH, PNPO, AGXT | L3MBTL1 1830/4885HRH3 3323/4885HCRTR1 1657/4885 |
| US-20230089374-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | XDH, PNPO, AGXT | L3MBTL1 1830/4885HRH3 3323/4885HCRTR1 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.