Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29673862 | 0.91 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29673846 | 0.91 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL25335984 | 0.90 | CYP2D6 (0.68) | POLBSMN1; SMN2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10519203 | 0.87 | POLB (0.57) | POLBSMN1; SMN2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10422930 | 0.83 | CASP1 (0.53) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL10422931 | 0.83 | CASP1 (0.53) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL29699722 | 0.81 | ALDH1A1 (0.60) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29699752 | 0.81 | ALDH1A1 (0.60) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8577834 | 0.80 | POLB (0.63) | POLBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7904484 | 0.80 | SMN1; SMN2 (0.69) | SMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685473-A | 5-alkyl-2-pyrazole-oxazolidine-4-ketone derivative and application thereof | 杭州百新生物医药科技有限公司 | 2022-07-01 | — | — | CN | disclosed |