Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PMM2 | O15305 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985235 | 0.84 | CA2 (0.53) | TDP1ALDH1A1KMT2AMEN1NPY1R | |
| SCHEMBL31370978 | 0.84 | CA2 (0.53) | TDP1ALDH1A1KMT2AMEN1NPY1R | |
| SCHEMBL31370785 | 0.82 | KMT2A (0.39) | TDP1ALDH1A1KMT2AMEN1NPY1R | |
| SCHEMBL23857814 | 0.82 | TDP1 (0.42) | TDP1ALDH1A1KMT2AMEN1CA2 | |
| SCHEMBL27984848 | 0.82 | KMT2A (0.39) | TDP1ALDH1A1KMT2AMEN1NPY1R | |
| SCHEMBL9652726 | 0.80 | ALDH1A1 (0.64) | TDP1ALDH1A1KMT2AMEN1NPY1R | |
| SCHEMBL28829380 | 0.79 | ALDH1A1 (0.42) | TDP1ALDH1A1KMT2AMEN1NPY1R | |
| SCHEMBL2062279 | 0.79 | KMT2A (0.43) | TDP1ALDH1A1KMT2AMEN1NPY1R | |
| SCHEMBL17203017 | 0.79 | GPR35 (0.55) | TDP1ALDH1A1KMT2AMEN1CA2 | |
| SCHEMBL2505183 | 0.79 | CA9 (0.45) | TDP1ALDH1A1KMT2AMEN1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115175908-B | Aryl or heteroaryl pyridone or pyrimidinone derivatives, and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-115175908-A | Aryl or heteroaryl pyridone or pyrimidone derivative and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| WO-2022135591-A1 | ARYL OR HETEROARYL PYRIDONE OR PYRIMIDONE DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2022-06-30 | — | — | WO | disclosed |
| CN-114671866-A | Aryl or heteroaryl pyridone or pyrimidone derivative and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2022-06-28 | — | — | CN | disclosed |