Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778685 | 0.83 | ALDH1A1 (0.38) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL1644688 | 0.79 | ALDH1A1 (0.42) | HDAC4HDAC2HDAC8ALDH1A1HSD17B10 | |
| SCHEMBL29700227 | 0.75 | HNF4A (0.45) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL60283 | 0.73 | HDAC4 (0.65) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL30605196 | 0.73 | HDAC4 (0.65) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL9563677 | 0.72 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL8559182 | 0.71 | HDAC4 (0.62) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL3805586 | 0.71 | HDAC4 (0.62) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL275842 | 0.71 | HDAC4 (0.62) | HNF4AHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL9487300 | 0.71 | HDAC4 (0.62) | HNF4AHDAC4HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110683940-B | Method for converting dibenzo [ c, e ] [1,2] oxathiane-6-oxide compound | 中国科学院成都生物研究所 | 2022-07-01 | — | — | CN | disclosed |