Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | DBH | P09172 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563677 | 0.90 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10ALOX15TDP1 | |
| SCHEMBL29904876 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10ALOX15TDP1 | |
| SCHEMBL3337693 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10ALOX15TDP1 | |
| SCHEMBL11195204 | 0.81 | G6PD (0.40) | ALDH1A1HPGDHSD17B10ALOX15TDP1 | |
| SCHEMBL29700261 | 0.79 | HNF4A (0.44) | ALDH1A1HPGDHSD17B10TDP1MAPK1 | |
| SCHEMBL3195082 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10ALOX15TDP1 | |
| SCHEMBL5399716 | 0.78 | CA12 (0.36) | ALDH1A1HPGDHSD17B10ALOX15TDP1 | |
| SCHEMBL7938038 | 0.77 | CYP3A4 (0.39) | ALDH1A1HPGDHSD17B10ALOX15TDP1 | |
| SCHEMBL5329574 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10ALOX15TDP1 | |
| SCHEMBL11197707 | 0.75 | GPR35 (0.50) | ALDH1A1ALOX15TDP1LMNACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874785-A | High-heat-conductivity high-temperature-resistant insulating layer for instant metal electric heating tube and preparation method thereof | 广西师范大学 | 2023-10-13 | — | — | CN | claimed |
| CN-116874785-A | High-heat-conductivity high-temperature-resistant insulating layer for instant metal electric heating tube and preparation method thereof | 广西师范大学 | 2023-10-13 | — | — | CN | disclosed |
| EP-4143157-A1 | METHODS OF MANUFACTURE OF DIANHYDRIDES | Chaulagain, Mani (US) | 2023-03-08 | — | — | EP | disclosed |
| CN-111655787-B | Thermoplastic resin composition and molded article thereof | 大科能宇菱通株式会社 | 2022-11-08 | — | — | CN | disclosed |
| WO-2021252169-A1 | METHODS OF MANUFACTURE OF DIANHYDRIDES | CHAULAGAIN MANI (US) | 2021-12-16 | — | — | WO | disclosed |
| US-10799610-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2020-10-13 | — | — | US | disclosed |
| CN-107207848-B | Polycarbonate resin composition and optical molded article | 住化PC有限公司 | 2019-11-05 | — | — | CN | disclosed |
| US-10413632-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2019-09-17 | — | — | US | disclosed |
| CN-105013017-B | A kind of minimally invasive orthopaedics implant compositions | 爱本斯南京医疗器械有限公司 | 2019-08-16 | — | — | CN | disclosed |
| US-10292262-B2 | Reinforcing-plate-integrated flexible printed circuit board | KANEKA CORPORATION (JP) | 2019-05-14 | — | — | US | disclosed |
| US-4514357-A | INJECTION MOLDING OF A POLYCARBONATE RESIN AND PHOSPHORUS ESTER MIXTURE | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1985-04-30 | — | — | US | disclosed |
| EP-0133657-A2 | Thermoplastic composition and process | GENERAL ELECTRIC COMPANY (US) | 1985-03-06 | — | — | EP | disclosed |
| EP-0014515-B1 | HARDENABLE COMPOSITIONS, PROCESS TO MAKE A SHAPED ARTICLE THEREFROM AND DENTAL APPLIANCE COMPRISING IT | DENTSPLY INTERNATIONAL, INC. (US) | 1984-03-14 | — | — | EP | disclosed |
| US-4396476-A | ACRYLIC ESTER HOMO- AND COPOLYMERS; PROSTHETICS; DENISTRY; MOLDING MATERIALS | DENTSPLY RESEARCH & DEVELOPMENT CORPORATION (US) | 1983-08-02 | — | — | US | disclosed |
| US-4396377-A | BLEND OF CROSSLINKED POLYMER, POLYMERIZABLE MONOMER AND CROSSLINKING AGENT HARDENED INTO SHAPED BODY | DENTSPLY RESEARCH & DEVELOPMENT CORPORATION (US) | 1983-08-02 | — | — | US | disclosed |
| EP-0008492-B1 | METHOD FOR MANUFACTURE OF AROMATIC POLYESTER-POLYCARBONATE | MITSUBISHI KASEI CORPORATION (JP) | 1983-05-18 | — | — | EP | disclosed |
| EP-0059525-A2 | Dental compositions | DENTSPLY INTERNATIONAL, INC. (US) | 1982-09-08 | — | — | EP | disclosed |
| WO-1982002556-A1 | STABLE ONE ART DENTAL COMPOSITIONS EMPLOYING IPN TECHNOLOGY | DENTSPLY INT INC (US) | 1982-08-05 | — | — | WO | disclosed |
| EP-0032124-A2 | Process for producing a crosslinked polymerizate for dental purposes | DENTSPLY INTERNATIONAL, INC. (US) | 1981-07-15 | — | — | EP | disclosed |
| EP-0014515-A2 | Hardenable compositions, process to make a shaped article therefrom and dental appliance comprising it | DENTSPLY INTERNATIONAL, INC. (US) | 1980-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10799610-B2 | Cement products and methods of making and using the same | BHMT2, SHMT1, BHMT | ALDH1A1 844/4885HPGD 96/4885HSD17B10 908/4885 |
| US-10413632-B2 | Cement products and methods of making and using the same | BHMT2, SHMT1, BHMT | ALDH1A1 844/4885HPGD 96/4885HSD17B10 908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.