SCHEMBL29700706

SCHEMBL29700706

Cc1cccc([C@H](O)CC(=O)N(C)C)c1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
AOC3 Q16853 1/20 0.41
ACP3 P15309 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29700751 0.83 L3MBTL1 (0.42) L3MBTL1
SCHEMBL14609675 0.81 CYP26A1 (0.49) L3MBTL1TAAR1ACP3
SCHEMBL279936 0.81 CYP26A1 (0.49) L3MBTL1TAAR1ACP3
SCHEMBL30530341 0.81 AOC3 (0.52) AOC3
SCHEMBL29700721 0.80 ACHE (0.43)
SCHEMBL29700742 0.76 AOC3 (0.59) AOC3
SCHEMBL19399109 0.75 TAAR1 (0.44) TAAR1AOC3ACP3
SCHEMBL8284965 0.74 AOC3 (0.41) AOC3ACP3
SCHEMBL16765313 0.73 TAAR1 (0.48) TAAR1AOC3ACP3
SCHEMBL7787303 0.73 ACP3 (0.44) TAAR1AOC3ACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736134-B (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof 浙江工业大学台州研究院 2023-06-06 CN disclosed
CN-114736134-A (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof 浙江工业大学台州研究院 2022-07-12 CN disclosed