SCHEMBL29700751

SCHEMBL29700751

CN(C)C(=O)C[C@@H](O)c1cccc(Br)c1

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.42
CTSA P10619 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29700706 0.83 L3MBTL1 (0.43) L3MBTL1
SCHEMBL27633524 0.82 L3MBTL1 (0.49) L3MBTL1CTSA
SCHEMBL27633523 0.82 L3MBTL1 (0.49) L3MBTL1CTSA
SCHEMBL27897603 0.81 L3MBTL1 (0.40) L3MBTL1CTSA
SCHEMBL29700727 0.80 CYP1A2 (0.42)
SCHEMBL8771264 0.80 CTSA (0.51) L3MBTL1CTSA
SCHEMBL30530341 0.80 AOC3 (0.52)
SCHEMBL30605867 0.79 L3MBTL1 (0.43) L3MBTL1CTSA
SCHEMBL8770972 0.79 L3MBTL1 (0.43) L3MBTL1CTSA
SCHEMBL8770921 0.78 KCNA5 (0.50) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736134-B (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof 浙江工业大学台州研究院 2023-06-06 CN disclosed
CN-114736134-A (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof 浙江工业大学台州研究院 2022-07-12 CN disclosed