Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27553231 | 0.82 | AOC3 (0.56) | AOC3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL27553229 | 0.82 | AOC3 (0.56) | AOC3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL4478666 | 0.81 | FFAR1 (0.56) | AOC3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL4478662 | 0.81 | FFAR1 (0.56) | AOC3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL29700721 | 0.81 | ACHE (0.43) | — | |
| SCHEMBL29700728 | 0.79 | AOC3 (0.54) | AOC3HPGDALDH1A1MAPT | |
| SCHEMBL3443782 | 0.79 | L3MBTL1 (0.67) | AOC3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL29700738 | 0.79 | AOC3 (0.54) | AOC3ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5468798 | 0.79 | AOC3 (0.57) | AOC3TDP1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29700727 | 0.79 | CYP1A2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736134-B | (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof | 浙江工业大学台州研究院 | 2023-06-06 | — | — | CN | disclosed |
| CN-114736134-A | (R) -beta-hydroxyaryl propionamide derivative and preparation method thereof | 浙江工业大学台州研究院 | 2022-07-12 | — | — | CN | disclosed |