SCHEMBL4478666

SCHEMBL4478666

COc1ccc([C@@H](O)CC(=O)O)cc1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 8/20 0.56
KMT2A Q03164 2/20 0.55
ATM Q13315 1/20 0.55
AOC3 Q16853 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.53
LDHA P00338 1/20 0.49
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4478662 1.00 FFAR1 (0.56) FFAR1KMT2AATMAOC3L3MBTL1
SCHEMBL27553229 0.87 AOC3 (0.56) FFAR1KMT2AATMAOC3L3MBTL1
SCHEMBL27553231 0.87 AOC3 (0.56) FFAR1KMT2AATMAOC3L3MBTL1
SCHEMBL9696473 0.85 AKR1C3 (0.60) FFAR1L3MBTL1MAPT
SCHEMBL6484578 0.85 FFAR1 (0.66) FFAR1KMT2AATML3MBTL1LDHA
SCHEMBL5468798 0.84 AOC3 (0.57) FFAR1KMT2AAOC3L3MBTL1ALDH1A1
SCHEMBL3443782 0.84 L3MBTL1 (0.67) FFAR1AOC3L3MBTL1ALDH1A1MAPT
SCHEMBL2226074 0.83 L3MBTL1 (0.68) FFAR1KMT2AATML3MBTL1LDHA
SCHEMBL6807907 0.82 AOC3 (0.51) FFAR1KMT2AATMAOC3L3MBTL1
SCHEMBL8077839 0.82 LMNA (0.48) FFAR1KMT2AL3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7498431-B2 Process for the preparation of chiral azetidinones FRAMROZE BOMI PATEL 2009-03-03 US disclosed
US-20070129540-A1 Process for the preparation of chiral azetidinones OPUS ORGANICS PVT LIMITED (IN) 2007-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129540-A1 Process for the preparation of chiral azetidinones CYP1B1, ALDH7A1, CYP3A5 FFAR1 1950/4885KMT2A 4551/4885ATM 4381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.