Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606938 | 1.00 | CYP19A1 (0.55) | CYP19A1LMNACYP1A2CYP3A4CYP11B1 | |
| SCHEMBL27900809 | 0.82 | CYP19A1 (0.53) | CYP19A1LMNACYP1A2CYP3A4CYP11B1 | |
| SCHEMBL11878647 | 0.81 | CYP19A1 (0.51) | CYP19A1LMNACYP1A2CYP3A4CYP11B1 | |
| SCHEMBL28442672 | 0.81 | CYP19A1 (0.51) | CYP19A1LMNACYP1A2CYP3A4CYP11B1 | |
| SCHEMBL28803515 | 0.81 | CYP19A1 (0.51) | CYP19A1LMNACYP1A2CYP3A4CYP11B1 | |
| SCHEMBL10966679 | 0.77 | LMNA (0.51) | CYP19A1LMNACYP1A2CYP3A4CYP11B1 | |
| SCHEMBL74389 | 0.76 | KIF11 (0.61) | CYP19A1LMNACYP1A2CYP3A4CYP11B1 | |
| SCHEMBL29583584 | 0.76 | KIF11 (0.61) | CYP19A1LMNACYP1A2CYP3A4CYP11B1 | |
| SCHEMBL10551098 | 0.76 | CYP19A1 (0.53) | CYP19A1LMNACYP1A2CYP3A4CYP11B1 | |
| Bromide SCHEMBL10923256 | 0.76 | CYP19A1 (0.46) | CYP19A1LMNACYP1A2CYP3A4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685363-A | ROR gamma t regulator, preparation method and application thereof | 上海医药集团股份有限公司 | 2022-07-01 | — | — | CN | disclosed |