SCHEMBL29702010

SCHEMBL29702010

O=[N+]([O-])c1c(Cl)ccc(Cl)c1[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TSHR P16473 3/20 0.56
TDP1 Q9NUW8 3/20 0.52
HSD17B10 Q99714 1/20 0.52
MAPK1 P28482 1/20 0.44
VCAM1 P19320 5/20 0.43
CYP3A4 P08684 1/20 0.39
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7514813 1.00 ALDH1A1 (0.56) ALDH1A1TSHRTDP1HSD17B10MAPK1
SCHEMBL672105 0.88 TDP1 (0.59) ALDH1A1TSHRTDP1HSD17B10MAPK1
SCHEMBL30946523 0.88 TDP1 (0.59) ALDH1A1TSHRTDP1HSD17B10MAPK1
SCHEMBL10980919 0.87 TSHR (0.62) ALDH1A1TSHRTDP1HSD17B10MAPK1
SCHEMBL9422167 0.87 ALDH1A1 (0.50) ALDH1A1TSHRTDP1HSD17B10MAPK1
SCHEMBL8069993 0.86 ALDH1A1 (0.47) ALDH1A1TSHRTDP1HSD17B10VCAM1
SCHEMBL10455740 0.86 GPR35 (0.48) ALDH1A1TSHRTDP1HSD17B10MAPK1
SCHEMBL7784706 0.86 ALDH1A1 (0.56) ALDH1A1TSHRTDP1HSD17B10CYP3A4
SCHEMBL670917 0.83 TSHR (0.58) ALDH1A1TSHRTDP1HSD17B10MAPK1
SCHEMBL9139396 0.83 TSHR (0.46) ALDH1A1TSHRTDP1HSD17B10VCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621270-B Condensed ring aromatic compound and application thereof in electroluminescent device 清华大学 2024-04-12 CN disclosed
CN-114621269-A Fused aromatic compound and application thereof in electroluminescent device 清华大学 2022-06-14 CN disclosed
CN-114621270-A Fused aromatic compound and application thereof in electroluminescent device 清华大学 2022-06-14 CN disclosed