SCHEMBL672105

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30946523	1.00	TDP1 (0.59)	TDP1TSHRMAPK1ALDH1A1VCAM1
	Acetone SCHEMBL27645515	0.90	TDP1 (0.50)	TDP1TSHRMAPK1ALDH1A1VCAM1
	Alcohol SCHEMBL27912165	0.89	TDP1 (0.48)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL7514813	0.88	ALDH1A1 (0.56)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL29702010	0.88	ALDH1A1 (0.56)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL3302919	0.85	TSHR (0.56)	TDP1TSHRMAPK1ALDH1A1GPR35
	SCHEMBL2160036	0.84	TDP1 (0.69)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL2145586	0.84	TDP1 (0.69)	TDP1TSHRMAPK1ALDH1A1VCAM1
	SCHEMBL29918148	0.84	TDP1 (0.69)	TDP1TSHRMAPK1ALDH1A1VCAM1
	Fluoride SCHEMBL10977459	0.83	TDP1 (0.67)	TDP1TSHRMAPK1ALDH1A1VCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.