Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | PI4KA | P42356 | 5/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397656 | 1.00 | DYRK1A (0.59) | DYRK1API4KAPI4K2BPI4K2API4KB | |
| Hydrochloric Acid SCHEMBL3353317 | 0.98 | DYRK1A (0.57) | DYRK1API4KAPI4K2BPI4K2API4KB | |
| Formic Acid SCHEMBL31745015 | 0.89 | DYRK1A (0.49) | DYRK1API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL3386908 | 0.74 | DYRK1A (0.59) | DYRK1AMAP4K4EIF4EMKNK1MKNK2 | |
| SCHEMBL2078428 | 0.74 | DYRK1A (0.59) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL32425027 | 0.74 | DYRK1A (1.00) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL23158613 | 0.74 | DYRK1A (0.64) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL1056424 | 0.74 | DYRK1A (0.59) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL8223 | 0.74 | DYRK1A (1.00) | DYRK1AEIF4EMKNK1MKNK2IRAK4 | |
| SCHEMBL13186164 | 0.74 | DYRK1A (0.59) | DYRK1AEIF4EMKNK1MKNK2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | claimed |
| US-12195468-B2 | TLR7 agonist for treating colorectal cancer and pharmaceutical combination thereof | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2025-01-14 | — | — | US | disclosed |
| CN-112823159-B | Aromatic heterocyclic compounds with kinase inhibitory activity | 上海轶诺药业有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115707705-A | Aromatic heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-02-21 | — | — | CN | disclosed |
| US-20220235053-A1 | TLR7 AGONIST FOR TREATING COLORECTAL CANCER AND PHARMACEUTICAL COMBINATION THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220235053-A1 | TLR7 AGONIST FOR TREATING COLORECTAL CANCER AND PHARMACEUTICAL COMBINATION THEREOF | TLR7, TLR9, TLR1 | DYRK1A 801/4885PI4KA 952/4885PI4K2B 1447/4885 |
| US-12195468-B2 | TLR7 agonist for treating colorectal cancer and pharmaceutical combination thereof | TLR7, TLR9, TLR1 | DYRK1A 801/4885PI4KA 952/4885PI4K2B 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.