Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | GLA | P06280 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.72 |
| ▸ | RELA | Q04206 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.51 |
| ▸ | GRM5 | P41594 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7884767 | 1.00 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL4238032 | 0.86 | RAB9A (0.76) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL29703258 | 0.86 | RAB9A (0.76) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL30088977 | 0.85 | RAB9A (0.73) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL29710433 | 0.84 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL28766363 | 0.84 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL4233263 | 0.84 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL1902033 | 0.84 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL7884958 | 0.84 | SMN1; SMN2 (0.72) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL29703282 | 0.84 | SMN1; SMN2 (0.72) | NPC1RAB9ASMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114560814-B | Synthesis method of substituted 2, 3-naphthyridine ketone compound | 天津理工大学 | 2023-10-20 | — | — | CN | disclosed |
| US-20220235011-A1 | PHTHALAZINONE COMPOUNDS AND USE THEREOF | ST PHARM CO., LTD. (KR) | 2022-07-28 | — | — | US | disclosed |
| CN-114560814-A | Synthesis method of substituted 2, 3-phthalazinone compound | 天津理工大学 | 2022-05-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220235011-A1 | PHTHALAZINONE COMPOUNDS AND USE THEREOF | SIRT6, SIRT1, SIRT2 | NPC1 1087/4885RAB9A 1699/4885SMN1; SMN2 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.