Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23013511 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HPGDNPSR1HSD17B10ALOX5 | |
| SCHEMBL23023679 | 0.87 | SLC34A1 (0.43) | ALDH1A1HPGDHSD17B10ALOX5KDM4E | |
| SCHEMBL23013548 | 0.85 | DHODH (0.41) | ALDH1A1HSD17B10KDM4ETGFBR1LMNA | |
| SCHEMBL29703800 | 0.85 | DHODH (0.41) | ALDH1A1HSD17B10KDM4ETGFBR1LMNA | |
| SCHEMBL25150706 | 0.85 | DGAT1 (0.45) | ALDH1A1HPGDNPSR1HSD17B10ALOX5 | |
| SCHEMBL29939181 | 0.85 | DGAT1 (0.45) | ALDH1A1HPGDNPSR1HSD17B10ALOX5 | |
| SCHEMBL29939563 | 0.84 | JAK2 (0.47) | ALDH1A1HPGDNPSR1HSD17B10ALOX5 | |
| SCHEMBL29939586 | 0.82 | DGAT1 (0.55) | DGAT1SOAT1 | |
| SCHEMBL25150512 | 0.82 | DGAT1 (0.55) | DGAT1SOAT1 | |
| SCHEMBL31277518 | 0.81 | EGFR (0.56) | ALDH1A1HPGDNPSR1HSD17B10ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555604-B | Pharmaceutical compounds | 辉瑞公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-114555604-A | Pharmaceutical compounds | 瑞威有限公司 | 2022-05-27 | — | — | CN | disclosed |