Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 17/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25150512 | 1.00 | DGAT1 (0.55) | DGAT1SOAT1 | |
| SCHEMBL25150706 | 0.92 | DGAT1 (0.45) | DGAT1SOAT1 | |
| SCHEMBL29939181 | 0.92 | DGAT1 (0.45) | DGAT1SOAT1 | |
| SCHEMBL29703828 | 0.86 | SMPD3 (0.41) | DGAT1SOAT1 | |
| SCHEMBL23014103 | 0.86 | SMPD3 (0.41) | DGAT1SOAT1 | |
| SCHEMBL23013511 | 0.82 | ALDH1A1 (0.44) | DGAT1SOAT1 | |
| SCHEMBL29703797 | 0.82 | ALDH1A1 (0.44) | DGAT1SOAT1 | |
| SCHEMBL25150575 | 0.81 | SMPD3 (0.42) | DGAT1SOAT1 | |
| SCHEMBL23013507 | 0.81 | PIK3CA (0.48) | DGAT1SOAT1 | |
| SCHEMBL23013299 | 0.78 | KMT2A (0.36) | DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12227507-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2025-02-18 | — | — | US | disclosed |
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
| US-20220324873-A1 | PHARMACEUTICAL COMPOUNDS | PFIZER INC. | 2022-10-13 | — | — | US | disclosed |
| US-20220306639-A1 | PHARMACEUTICAL COMPOUNDS | PFIZER INC. | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12227507-B2 | Pharmaceutical compounds | CHRNA6, GABRA6, CHRNA7 | DGAT1 4476/4885SOAT1 1440/4885 |
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | DGAT1 4349/4885SOAT1 1663/4885 |
| US-20220306639-A1 | PHARMACEUTICAL COMPOUNDS | CHRNA6, GABRA6, CHRNA7 | DGAT1 4476/4885SOAT1 1440/4885 |
| US-20220324873-A1 | PHARMACEUTICAL COMPOUNDS | GABRA6, CNR1, CHRNA6 | DGAT1 4382/4885SOAT1 1896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.