Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 2/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14658943 | 1.00 | TAAR1 (0.38) | TAAR1EGFRUCHL1CSF1RHMGCR | |
| SCHEMBL14659310 | 0.85 | EGFR (0.36) | EGFR | |
| SCHEMBL16637155 | 0.84 | LPL (0.36) | P2RX7ROCK1LPLLIPGCXCR2 | |
| SCHEMBL18819293 | 0.83 | LPL (0.34) | EGFRLPLLIPG | |
| SCHEMBL14406854 | 0.83 | EGFR (0.39) | EGFRCSF1RLPLLIPGLMNA | |
| SCHEMBL18805560 | 0.80 | JAK2 (0.36) | UCHL1ROCK1LPLLIPGCXCR2 | |
| SCHEMBL17258894 | 0.79 | DGAT1 (0.40) | NPC1MAPK1 | |
| SCHEMBL29652912 | 0.79 | DGAT1 (0.40) | NPC1MAPK1 | |
| SCHEMBL28598599 | 0.79 | EGFR (0.44) | TAAR1EGFRCSF1RLPLLIPG | |
| SCHEMBL29470635 | 0.79 | ROCK1 (0.35) | ROCK1LPLLIPGCXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110573508-B | Fused imidazo-piperidine JAK inhibitor compounds | 施万生物制药研发IP有限责任公司 | 2022-07-05 | — | — | CN | disclosed |