Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.41 |
| ▸ | CA1 | P00915 | 12/20 | 0.41 |
| ▸ | CA9 | Q16790 | 12/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31381519 | 0.86 | JAK2 (0.39) | CA2CA1CA9CA4CA6 | |
| SCHEMBL3717934 | 0.86 | CA1 (0.45) | CA2CA1CA9CA4CA6 | |
| SCHEMBL31127486 | 0.85 | CA2 (0.44) | CA2CA1CA9CA4CA6 | |
| SCHEMBL6608093 | 0.85 | CA2 (0.44) | CA2CA1CA9CA4CA6 | |
| SCHEMBL20298060 | 0.84 | CA2 (0.41) | CA2CA1CA9CA4CA6 | |
| SCHEMBL31258294 | 0.84 | CA2 (0.40) | CA2CA1CA9CA4CA6 | |
| SCHEMBL24669737 | 0.83 | CA2 (0.40) | CA2CA1CA9CA4CA6 | |
| SCHEMBL17441815 | 0.83 | CDK2 (0.47) | CA2CA1CA9CA4CA6 | |
| SCHEMBL11927624 | 0.79 | LPL (0.44) | CA2CA1CA9JAK2BTK | |
| SCHEMBL28999166 | 0.75 | CA1 (0.41) | CA2CA1CA9CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025122956-A1 | COMBINATION THERAPY | VIVACE THERAPEUTICS, INC. (US) | 2025-06-12 | — | — | WO | disclosed |
| EP-4281073-A1 | COMBINATION OF A 3-(IMIDAZOL-4-YL)-4-(AMINO)-BENZENESULFONAMIDE TEAD INHIBITOR WITH AN EGFR INHIBITOR AND/OR MEK INHIBITOR FOR USE IN THE TREATMENT OF LUNG CANCER | Ikena Oncology, Inc. (US) | 2023-11-29 | — | — | EP | disclosed |
| WO-2022159986-A1 | COMBINATION OF A 3-(IMIDAZOL-4-YL)-4-(AMINO)-BENZENESULFONAMIDE TEAD INHIBITOR WITH AN EGFR INHIBITOR AND/OR MEK INHIBITOR FOR USE IN THE TREATMENT OF LUNG CANCER | Ikena Oncology, Inc. (US) | 2022-07-28 | — | — | WO | disclosed |