SCHEMBL6608093

SCHEMBL6608093

CC1(C)OB(c2ccccc2S(N)(=O)=O)OC1(C)C

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 18/20 0.44
CA9 Q16790 17/20 0.44
CA1 P00915 16/20 0.44
CA12 O43570 5/20 0.44
CA6 P23280 4/20 0.44
CA5A P35218 4/20 0.44
CA4 P22748 3/20 0.44
CA7 P43166 3/20 0.44
CA5B Q9Y2D0 3/20 0.44
CA14 Q9ULX7 2/20 0.44
CA3 P07451 1/20 0.44
CYP2C9 P11712 1/20 0.41
LPL P06858 1/20 0.40
LIPG Q9Y5X9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31127486 1.00 CA2 (0.44) CA2CA9CA1CA12CA6
SCHEMBL20298060 0.85 CA2 (0.41) CA2CA9CA1CA12CA6
SCHEMBL29704142 0.85 CA2 (0.41) CA2CA9CA1CA12CA6
SCHEMBL14258661 0.84 LPL (0.41) CA2CA9CA1CA12CA6
SCHEMBL24669737 0.84 CA2 (0.40) CA2CA9CA1CA12CA6
SCHEMBL17441815 0.84 CDK2 (0.47) CA2CA9CA1CA12CA6
SCHEMBL31618338 0.83 ELANE (0.41) CA2CA9CA1CA12CA6
SCHEMBL17441884 0.81 LDHA (0.47) CA2CA9CA1CA12CA6
SCHEMBL29403818 0.80 ALDH1A1 (0.42) CA2CA9CA1CA12CA6
SCHEMBL6034212 0.80 ALDH1A1 (0.42) CA2CA9CA1CA12CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023078271-A1 AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF 上海旭成医药科技有限公司 2023-05-11 WO disclosed
EP-2751093-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Infinity Pharmaceuticals, Inc. (US) 2014-07-09 EP disclosed
WO-2013032591-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INFINITY PHARMACEUTICALS INC. (US) 2013-03-07 WO disclosed
EP-1414801-A1 ARYLAMINES FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH GSK-3 AstraZeneca AB (SE) 2004-05-06 EP disclosed
WO-2003004472-A1 ARYLAMINES FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH GSK-3 ASTRAZENECA AB (SE) 2003-01-16 WO disclosed