Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19644534 | 1.00 | CNR2 (0.46) | CNR2CNR1ALDH1A1ALOX15HPGD | |
| SCHEMBL18548025 | 0.82 | DGAT2 (0.40) | CNR2CNR1ALDH1A1HPGDRPS6KB1 | |
| SCHEMBL31632983 | 0.82 | AXL (0.42) | CNR2CNR1ALDH1A1ALOX15HPGD | |
| SCHEMBL31522407 | 0.80 | ALDH1A1 (0.47) | CNR2CNR1ALDH1A1ALOX15HPGD | |
| SCHEMBL30676733 | 0.80 | ELANE (0.53) | CNR2CNR1KDM4CSSTR4OPRK1 | |
| SCHEMBL29121557 | 0.80 | ELANE (0.53) | CNR2CNR1KDM4CSSTR4OPRK1 | |
| SCHEMBL29704418 | 0.77 | PTGER4 (0.40) | ALDH1A1ALOX15HPGDMGLLHSD17B10 | |
| SCHEMBL19657727 | 0.77 | PTGER4 (0.40) | ALDH1A1ALOX15HPGDMGLLHSD17B10 | |
| SCHEMBL20594787 | 0.77 | ALDH1A1 (0.43) | CNR2ALDH1A1ALOX15HPGDHSD17B10 | |
| SCHEMBL19644454 | 0.76 | OPRK1 (0.38) | ALDH1A1ALOX15HPGDMGLLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028617-A | Heterocyclic inhibitors of CBP/EP300 and their use in the treatment of cancer | 基因泰克公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-109476641-B | Heterocyclic inhibitors of CBP/EP300 and their use in the treatment of cancer | 基因泰克公司 | 2022-07-05 | — | — | CN | disclosed |