Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20521236 | 1.00 | ATM (0.43) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL30791431 | 0.90 | HCAR3 (0.42) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL31152812 | 0.88 | ATM (0.44) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL31152809 | 0.88 | ATM (0.44) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL2610943 | 0.88 | ATM (0.44) | ATMTDP1SNCAMAPTALDH1A1 | |
| SCHEMBL27804034 | 0.86 | HSPB1 (0.40) | TDP1MAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL10136028 | 0.85 | TSHR (0.45) | MAPTALDH1A1HTTL3MBTL1HCAR3 | |
| SCHEMBL27782513 | 0.85 | SIRT5 (0.42) | SNCAMAPTALDH1A1HTTAR | |
| SCHEMBL27804074 | 0.85 | HSPB1 (0.39) | TDP1SNCAMAPTALDH1A1HTT | |
| SCHEMBL26919903 | 0.85 | ATM (0.41) | ATMTDP1SNCAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110475777-B | Novel pyrido [2,3-b ] indole compounds for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | disclosed |