Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29705155 | 0.84 | LMNA (0.48) | ELANETDP1ALDH1A1ATMHPGD | |
| SCHEMBL20240716 | 0.82 | TDP1 (0.59) | ELANETDP1ALDH1A1HPGDTSHR | |
| SCHEMBL28330548 | 0.79 | CNR2 (0.54) | ELANEALDH1A1HPGDCNR2KDM4E | |
| SCHEMBL28329422 | 0.76 | ELANE (0.58) | ELANETDP1ALDH1A1HPGDTSHR | |
| SCHEMBL7954868 | 0.76 | ELANE (0.56) | ELANETDP1ALDH1A1ATMHTR3A | |
| SCHEMBL7966469 | 0.76 | ELANE (0.56) | ELANETDP1ALDH1A1ATMHTR3A | |
| SCHEMBL7953666 | 0.76 | ELANE (0.58) | ELANETDP1HTR3ATSHRMAPK1 | |
| SCHEMBL7946372 | 0.75 | ELANE (0.55) | ELANETDP1HTR3AMAPK1KDM4E | |
| SCHEMBL5962115 | 0.75 | LMNA (0.48) | ALDH1A1ATMHPGDTSHRLMNA | |
| SCHEMBL20520937 | 0.75 | LMNA (0.48) | ALDH1A1ATMHPGDTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110475777-B | Novel pyrido [2,3-b ] indole compounds for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | disclosed |