Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23042416 | 1.00 | SPR (0.34) | SPRNPC1DGAT1MAPT | |
| SCHEMBL24566831 | 0.85 | NPC1 (0.32) | NPC1DGAT1 | |
| SCHEMBL3300284 | 0.85 | DGAT1 (0.39) | NPC1DGAT1 | |
| SCHEMBL3299844 | 0.85 | NPC1 (0.33) | NPC1DGAT1 | |
| SCHEMBL19023210 | 0.85 | SPR (0.36) | SPRNPC1DGAT1MAPT | |
| SCHEMBL29729389 | 0.84 | NPC1 (0.31) | SPRNPC1DGAT1 | |
| SCHEMBL29705308 | 0.83 | DGAT1 (0.33) | NPC1DGAT1 | |
| SCHEMBL27215304 | 0.83 | DGAT1 (0.40) | NPC1DGAT1MAPT | |
| SCHEMBL16516690 | 0.83 | NPC1 (0.35) | NPC1DGAT1MAPT | |
| SCHEMBL27215150 | 0.83 | NPC1 (0.33) | NPC1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |
| EP-4017875-A1 | THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS | Terns Pharmaceuticals, Inc. (US) | 2022-06-29 | — | — | EP | disclosed |