Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.35 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | CLK2 | P49760 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20674185 | 1.00 | FGFR1 (0.40) | FGFR1FGFR2FGFR3PIK3C3BRAF | |
| SCHEMBL12344590 | 0.74 | PIK3C3 (0.37) | FGFR1PIK3C3BRAFCHEK1AKT1 | |
| SCHEMBL29705478 | 0.73 | MAPT (0.50) | FGFR1PIK3C3BRAFCHEK1AKT1 | |
| SCHEMBL11982852 | 0.73 | PIK3C3 (0.36) | FGFR1PIK3C3BRAFCHEK1AKT1 | |
| SCHEMBL15243458 | 0.73 | NOS1 (0.50) | FGFR1PIK3C3BRAFCHEK1AKT1 | |
| SCHEMBL10329 | 0.73 | DYRK1A (0.50) | FGFR1PIK3C3CHEK1MAP4K4CLK2 | |
| SCHEMBL3429629 | 0.73 | PIK3C3 (0.36) | FGFR1PIK3C3BRAFCHEK1AKT1 | |
| SCHEMBL1496196 | 0.73 | MAPT (0.50) | FGFR1PIK3C3BRAFCHEK1AKT1 | |
| SCHEMBL27077213 | 0.73 | PIK3C3 (0.36) | FGFR1PIK3C3BRAFCHEK1AKT1 | |
| SCHEMBL2619214 | 0.73 | CCR1 (0.46) | PIK3C3CHEK1AKT1PIK3CAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076632-A1 | COMPOUNDS AND USES THEREOF | FIBROCOR THERAPEUTICS INC. (CA) | 2025-04-17 | — | — | WO | disclosed |
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |