Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496196 | 1.00 | MAPT (0.50) | MAPTKDM4EMEN1KMT2AROCK2 | |
| Hydrochloric Acid SCHEMBL16910254 | 0.98 | MAPT (0.48) | MAPTKDM4EMEN1KMT2AROCK2 | |
| SCHEMBL12344590 | 0.74 | PIK3C3 (0.37) | MAPTKDM4EMEN1KMT2AROCK2 | |
| SCHEMBL29930749 | 0.73 | KIT (0.55) | PIK3C3PIK3CAMAP4K4NTRK1DYRK1A | |
| SCHEMBL11982852 | 0.73 | PIK3C3 (0.36) | MAPTKDM4EMEN1KMT2AROCK2 | |
| SCHEMBL20674185 | 0.73 | FGFR1 (0.40) | ROCK2ROCK1ALDH1A1HIF1ACHEK1 | |
| SCHEMBL3429629 | 0.73 | PIK3C3 (0.36) | MAPTKDM4EMEN1KMT2AROCK2 | |
| SCHEMBL10329 | 0.73 | DYRK1A (0.50) | MAPTKDM4EKMT2AROCK2ROCK1 | |
| SCHEMBL29705375 | 0.73 | FGFR1 (0.40) | ROCK2ROCK1ALDH1A1HIF1ACHEK1 | |
| SCHEMBL15243458 | 0.73 | NOS1 (0.50) | MAPTKDM4EMEN1KMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546137-A | Preparation method and application of 5, 6-fused bicyclic benzamide derivative | 重庆大学 | 2024-08-27 | — | — | CN | claimed |
| US-20240336592-A1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA PLC (GB) | 2024-10-10 | — | — | US | disclosed |
| CN-118546137-A | Preparation method and application of 5, 6-fused bicyclic benzamide derivative | 重庆大学 | 2024-08-27 | — | — | CN | disclosed |
| CN-117756805-A | Pteridinone derivatives as RSK inhibitors and their use | 华东师范大学 | 2024-03-26 | — | — | CN | disclosed |
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336592-A1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | DDR1, DDR2, DDRGK1 | MAPT 3438/4885KDM4E 2654/4885MEN1 3573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.