Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848806 | 1.00 | HDAC4 (0.49) | HDAC4SLC6A2SLC6A4OPRM1LMNA | |
| SCHEMBL2847573 | 0.97 | HDAC4 (0.46) | HDAC4SLC6A2SLC6A4OPRM1OPRK1 | |
| SCHEMBL13764638 | 0.94 | OPRK1 (0.44) | SLC6A2SLC6A4OPRM1OPRK1OPRD1 | |
| SCHEMBL29731283 | 0.87 | CYP2C19 (0.45) | LMNATSHRTDP1OPRK1 | |
| SCHEMBL27078112 | 0.87 | CYP2C19 (0.45) | LMNATSHRTDP1OPRK1 | |
| SCHEMBL17147282 | 0.84 | HDAC4 (0.68) | HDAC4LMNATSHRNPSR1TDP1 | |
| SCHEMBL30683829 | 0.83 | ADAM17 (0.53) | HDAC4SLC6A2SLC6A4OPRM1TSHR | |
| SCHEMBL2846322 | 0.83 | ADAM17 (0.53) | HDAC4SLC6A2SLC6A4OPRM1TSHR | |
| SCHEMBL4942383 | 0.83 | TSHR (0.56) | HDAC4SLC6A2SLC6A4LMNATSHR | |
| SCHEMBL28790841 | 0.83 | HDAC4 (0.51) | HDAC4OPRM1LMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |