Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23164255 | 1.00 | ALOX5 (0.39) | ALOX5CYP11B2POLBHCAR2KDM4E | |
| SCHEMBL16196153 | 0.89 | CYP11B2 (0.45) | CYP11B2POLBHCAR2KDM4EALDH1A1 | |
| SCHEMBL23163988 | 0.82 | ITGA4 (0.39) | POLBHCAR2KDM4EALDH1A1HPGD | |
| SCHEMBL332753 | 0.78 | ALOX5 (0.50) | ALOX5HCAR2HRH3ALDH1A1HDAC3 | |
| SCHEMBL31115373 | 0.77 | POLB (0.37) | CYP11B2POLBHCAR2KDM4EALDH1A1 | |
| SCHEMBL15349227 | 0.76 | HDAC1 (0.53) | ALOX5HRH3ALDH1A1HDAC3HDAC1 | |
| SCHEMBL16195680 | 0.76 | CYP11B2 (0.42) | ALOX5CYP11B2POLBHCAR2KDM4E | |
| SCHEMBL13048695 | 0.74 | POLB (0.47) | POLBHCAR2KDM4EALDH1A1HPGD | |
| SCHEMBL17686064 | 0.73 | CYP11B1 (0.38) | CYP11B2POLBHCAR2KDM4EALDH1A1 | |
| SCHEMBL23972281 | 0.73 | POLB (0.34) | CYP11B2POLBHCAR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |