Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23164192 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ACACBTP53HTTALOX5 | |
| SCHEMBL23164193 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ACACBTP53HTTALOX5 | |
| SCHEMBL23164208 | 0.93 | ALOX5 (0.47) | ALDH1A1ACACBTP53HTTALOX5 | |
| SCHEMBL23164209 | 0.93 | ALOX5 (0.47) | ALDH1A1ACACBTP53HTTALOX5 | |
| SCHEMBL23164044 | 0.92 | ACACB (0.50) | ACACBTSHRSMN1; SMN2SRD5A2RXRA | |
| SCHEMBL23164048 | 0.92 | ACACB (0.50) | ACACBTSHRSMN1; SMN2SRD5A2RXRA | |
| SCHEMBL23163958 | 0.90 | RXRA (0.52) | ALDH1A1ACACBTP53HTTSMN1; SMN2 | |
| SCHEMBL23163961 | 0.90 | RXRA (0.52) | ALDH1A1ACACBTP53HTTSMN1; SMN2 | |
| SCHEMBL28749473 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TP53HTTALOX5SMN1; SMN2 | |
| SCHEMBL29705535 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TP53HTTALOX5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |