Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 11/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | L3MBTL4 | Q8NA19 | 3/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.43 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24185682 | 0.88 | L3MBTL1 (0.58) | L3MBTL3L3MBTL1HRH3L3MBTL4KCNH2 | |
| SCHEMBL2377708 | 0.87 | POLB (0.54) | L3MBTL1HRH3 | |
| SCHEMBL2967406 | 0.84 | HRH3 (0.60) | L3MBTL3L3MBTL1HRH3L3MBTL4KCNH2 | |
| SCHEMBL2966380 | 0.82 | HRH3 (0.65) | L3MBTL3L3MBTL1HRH3KCNH2 | |
| SCHEMBL24185702 | 0.81 | L3MBTL3 (0.63) | L3MBTL3L3MBTL1HRH3L3MBTL4MBTD1 | |
| SCHEMBL31262623 | 0.80 | L3MBTL1 (0.50) | L3MBTL3L3MBTL1HRH3KCNH2 | |
| SCHEMBL1427022 | 0.76 | ALDH1A1 (0.57) | L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL642288 | 0.76 | ALDH1A1 (0.55) | L3MBTL3L3MBTL1HRH3KCNH2 | |
| SCHEMBL1872354 | 0.75 | ALDH1A1 (0.59) | L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL24185769 | 0.75 | ALDH1A1 (0.46) | L3MBTL3L3MBTL1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732548-B | N2-carbamyl aromatic ring-2-aminopyrimidine derivatives and medical application thereof | 浙江大学 | 2022-06-17 | — | — | CN | disclosed |