Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20073787 | 1.00 | SLC6A5 (0.43) | SLC6A5CYP2D6CHRM1CCR2KCNH2 | |
| SCHEMBL20073792 | 0.91 | CCR2 (0.42) | CYP2D6CHRM1CCR2KCNH2CTSL | |
| SCHEMBL20066223 | 0.90 | CYP2D6 (0.47) | CYP2D6CHRM1CCR2KCNH2CTSL | |
| SCHEMBL20073802 | 0.90 | CYP2D6 (0.47) | CYP2D6CHRM1CCR2KCNH2CTSL | |
| SCHEMBL20073962 | 0.89 | CYP2D6 (0.51) | SLC6A5CYP2D6CHRM1MEN1KMT2A | |
| SCHEMBL20073966 | 0.89 | CYP2D6 (0.51) | SLC6A5CYP2D6CHRM1MEN1KMT2A | |
| SCHEMBL20073789 | 0.89 | KMT2A (0.48) | CYP2D6CHRM1CCR2KCNH2MEN1 | |
| SCHEMBL28310378 | 0.88 | CTSL (0.41) | CYP2D6CHRM1CCR2KCNH2MEN1 | |
| SCHEMBL20073797 | 0.84 | CYP2D6 (0.54) | SLC6A5CYP2D6CHRM1CCR2KCNH2 | |
| SCHEMBL20075017 | 0.84 | CYP2D6 (0.54) | SLC6A5CYP2D6CHRM1CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834407-B2 | Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-12-05 | — | — | US | disclosed |
| US-20220213034-A1 | SUBSTITUTED CYCLOHEXANES AS MUSCARINIC M1 RECEPTOR AND/OR M4 RECEPTOR AGONISTS | NXERA PHARMA UK LIMITED (GB) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213034-A1 | SUBSTITUTED CYCLOHEXANES AS MUSCARINIC M1 RECEPTOR AND/OR M4 RECEPTOR AGONISTS | CHRM1, CHRM2, CHRM4 | SLC6A5 4141/4885CYP2D6 261/4885CHRM1 1/4885 |
| US-11834407-B2 | Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists | CHRM1, CHRM2, CHRM4 | SLC6A5 4141/4885CYP2D6 261/4885CHRM1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.