SCHEMBL29711331

SCHEMBL29711331

COc1c(O)c2c(=O)cc(OC)c3c4c(OC)cc(=O)c5c(O)c(OC)c(CC(C)OC(=O)c6ccccc6)c(c(c1CC(C)O)c23)c54

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTNNB1 P35222 8/20 0.76
▸ TCF4 P15884 7/20 0.76
▸ MAPT P10636 3/20 0.76
▸ CDH1 P12830 2/20 0.76
▸ APC P25054 2/20 0.76
▸ TCF7L2 Q9NQB0 2/20 0.76
▸ THRB P10828 2/20 0.76
▸ SMN1; SMN2 Q16637 2/20 0.76
▸ SYK P43405 1/20 0.76
▸ KMT2A Q03164 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ RECQL P46063 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ KIT P10721 1/20 0.35
▸ LMNA P02545 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29711243 0.96 CTNNB1 (0.81) CTNNB1TCF4MAPTCDH1APC
SCHEMBL29711326 0.88 CTNNB1 (0.78) CTNNB1TCF4MAPTCDH1APC
SCHEMBL29525736 0.87 CTNNB1 (1.00) CTNNB1TCF4MAPTCDH1APC
SCHEMBL29372562 0.87 CTNNB1 (1.00) CTNNB1TCF4MAPTCDH1APC
SCHEMBL29711267 0.84 CTNNB1 (0.68) CTNNB1TCF4MAPTCDH1APC
SCHEMBL29929662 0.84 CTNNB1 (0.68) CTNNB1TCF4MAPTCDH1APC
SCHEMBL31134383 0.83 CTNNB1 (0.64) CTNNB1TCF4MAPTCDH1APC
SCHEMBL16500263 0.81 CTNNB1 (0.73) CTNNB1TCF4MAPTCDH1APC
Calphostin C SCHEMBL15185703 0.74 CTNNB1 (0.79) CTNNB1TCF4MAPTCDH1APC
SCHEMBL29369377 0.69 CTNNB1 (1.00) CTNNB1TCF4MAPTCDH1APC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
EP-2841109-B1 PRODRUGS OF HYDROXYL-COMPRISING DRUGS ASCENDIS PHARMA AS (DK) 2026-04-15 — — EP disclosed
US-20250203557-A1 SATELLITE-ASSISTED USER EQUIPMENT (UE) LOCATION TECHNIQUES INTEL CORP (US) 2025-06-19 — — US disclosed
US-20250161394-A1 Compositions Comprising Kavalactones NATURAL EXTRACTION SYS LLC (US) 2025-05-22 — — US disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 — — EP disclosed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 — — US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 — — US disclosed
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels ASCENDIS PHARMA A/S (DK) 2023-04-20 — — US disclosed
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels ASCENDIS PHARMA A/S (DE) 2023-01-24 — — US disclosed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO disclosed
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels PLG, PHYKPL, PLOD3 CTNNB1 4291/4885TCF4 4868/4885MAPT 1671/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 CTNNB1 3806/4885TCF4 4812/4885MAPT 3354/4885
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels PLG, PHYKPL, PLOD3 CTNNB1 4291/4885TCF4 4868/4885MAPT 1671/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 CTNNB1 3806/4885TCF4 4812/4885MAPT 3354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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